Protein Alignment bap and HLX

DIOPT Version :10

• Sequence 1: NP_732637.1
• Gene: bap / 42537
• FlyBaseID: FBgn0004862
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_068777.1
• Gene: HLX / 3142
• HGNCID: 4978
• Length: 488
• Species: Homo sapiens
• Alignment Length: 218
• Identity: 63/218 - (28%)
• Similarity: 92/218 - (42%)
• Gaps: 41/218 - (18%)

  Fly    31 TRSNPETRRMSSVDSEPEPEKLKPSSDRERSISKSPPL----CCRDL-GLYKLTQPKEIQPSARQ 90
            ||..|......|..: |..:.||...||..|....|.:    ..||| .|....:|..:..|..|
Human   154 TRVVPNPHHSGSAPA-PSSKDLKFGIDRILSAEFDPKVKEGNTLRDLTSLLTGGRPAGVHLSGLQ 217

  Fly    91 PSNYLQYYAAAMDNNNHHHQATGTSNSSAADYMQRKLAYFGSTLAAPLDMRRCTSNDSDCDSPPP 155
            ||  ...:.|::|..|.........||:..:.:|.:   |..|...|.
Human   218 PS--AGQFFASLDPINEASAILSPLNSNPRNSVQHQ---FQDTFPGPY----------------- 260

  Fly   156 LSSSPSESPLSHDGSGLSRKKR---SRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTET 217
                   :.|:.|....:.|::   |||.||:.|...||:||..|:|::.|:|.::|..|.||:.
Human   261 -------AVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDA 318

  Fly   218 QVKIWFQNRRYK---TKRKQIQQ 237
            |||:||||||.|   :|..|.|:
Human   319 QVKVWFQNRRMKWRHSKEAQAQK 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeodomain	176..232	CDD:459649	28/61 (46%)
HLX	NP_068777.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..173		5/19 (26%)
		Homeodomain	273..333	CDD:459649	29/59 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	331..488		3/11 (27%)