DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bap and vsx1

DIOPT Version :9

Sequence 1:	NP_732637.1	Gene:	bap / 42537	FlyBaseID:	FBgn0004862	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_571408.1	Gene:	vsx1 / 30598	ZFINID:	ZDB-GENE-990415-205	Length:	344	Species:	Danio rerio

Alignment Length:	305	Identity:	66/305 - (21%)
Similarity:	108/305 - (35%)	Gaps:	112/305 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 TRRMSSVDSEPEPEKLKPS--SDRER---SISKSPPLCCRD-LGLYKLTQPKEIQP--------- 86
            |.|..:.|.:|: .||.||  .|:.|   |..:|......| |||....||.:..|
Zfish     2 TGREEATDEKPK-VKLYPSFGIDKSRLNGSGFRSKGFAITDLLGLESELQPHQSGPGAGPNGEGQ 65

  Fly    87 ------------------------SARQPSN---YLQYYAAAMDNNNHHHQATGTSNSSAADYMQ 124
                                    :|:||..   :|..:...:.:....|            :||
Zfish    66 SAAVGGFSFPGGSLPLGLGFLCSLAAQQPPGAPCFLPSHIPLLQSRTESH------------FMQ 118

  Fly   125 RKLAYFGSTLAAPLDMRRCTSNDSDCDSPPPLSSSPSESPLSHDGSGLSRKK-RSRAAFSHAQVF 188
            .            |:.:|...:|.||     ||...::.  .:.|:...||| |.|..|:..|:.
Zfish   119 N------------LEQQRDVYSDDDC-----LSGDRNDG--KNSGNSQKRKKRRHRTVFTSHQLE 164

  Fly   189 ELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQIQQHEAALLGASKRVPVQV 253
            |||:.|.:..|.....|..:|....|.|.::::||||||.|.::::.....::::
Zfish   165 ELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVM---------- 219

  Fly   254 LVREDGSTTYAHMAAPGAGHGLDPALINIYRHQLQLAYGGLPLPQ 298
                             |.:||..|::   ||       .:|||:
Zfish   220 -----------------AEYGLYGAMV---RH-------SIPLPE 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeobox	178..231	CDD:278475	19/52 (37%)
vsx1	NP_571408.1	Octapeptide motif	37..44		1/6 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	49..70		3/20 (15%)
		COG5576	101..>221	CDD:227863	35/177 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	127..156		10/35 (29%)
		Nuclear localization signal. /evidence=ECO:0000269\|PubMed:11331779	147..151		1/3 (33%)
		Homeobox	154..207	CDD:278475	19/52 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	273..344
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910