DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bap and rx1

DIOPT Version :9

Sequence 1:	NP_732637.1	Gene:	bap / 42537	FlyBaseID:	FBgn0004862	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_571300.2	Gene:	rx1 / 30472	ZFINID:	ZDB-GENE-990415-236	Length:	330	Species:	Danio rerio

Alignment Length:	343	Identity:	84/343 - (24%)
Similarity:	120/343 - (34%)	Gaps:	115/343 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 DSEPEPEKLKPSSDRERSISKSPPLCCRDLGLYKLTQPKEIQPSARQPSNYLQYYAAAMDNNNHH 108
            :|..||.||   ..|.:.....|||  ||              .:.||:               .
Zfish    67 ESLGEPGKL---DQRVQPYGHLPPL--RD--------------GSEQPT---------------F 97

  Fly   109 HQATGTSNSSAADYMQRKLAYFGSTLAAPLDMRRCTSNDSDCDSPPPLSSSPSESPLSHDGSGLS 173
            |.|...||....|        .|       |:|:...:|             |:||.|.||....
Zfish    98 HDADMFSNKCDGD--------LG-------DLRKAIESD-------------SKSPDSADGEQPK 134

  Fly   174 RK-KRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQIQQ 237
            :| :|:|..|:..|:.||||.|.:..|.....|.|:|..:.|.|.:|::||||||.|.:|::
Zfish   135 KKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMKVNLPEVRVQVWFQNRRAKWRRQE--- 196

  Fly   238 HEAALLGASKRVPVQVLVREDGSTTYAHMAAPGAGHGLDPALINIYRHQLQLAYG----GLPL-P 297
                              :.|.||...|          |..:::..|..:....|    .||| |
Zfish   197 ------------------KIDASTMKLH----------DSPMLSFNRPSMHPTVGPMNNSLPLDP 233

  Fly   298 QMQMPFPYFYPQHKVPQPIPPPTQSSSFVTASSASSSPVPIPIPGAVRPQRTP---CPSPNGQMM 359
            .:..|.....|.|.:| ....|||.........:..|| |.|:..:::|...|   ||.|.....
Zfish   234 WLPSPLSSATPVHSIP-GFMGPTQGLQTGYPGHSFLSP-PQPMAQSMQPMAPPPYQCPPPFTDKY 296

  Fly   360 SVESGAESVHSAAEDVDE 377
            .:           ||||:
Zfish   297 PL-----------EDVDQ 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeobox	178..231	CDD:278475	22/52 (42%)
rx1	NP_571300.2	Octapeptide motif	37..44
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	66..104		15/70 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	118..142		9/36 (25%)
		Homeobox	141..193	CDD:278475	22/51 (43%)
		OAR	302..318	CDD:281777	1/2 (50%)
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	306..319
		Nuclear localization signal. /evidence=ECO:0000255	312..316
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910