DRSC/TRiP Functional Genomics Resources

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Protein Alignment bap and NKX2-8

DIOPT Version :9

Sequence 1:NP_732637.1 Gene:bap / 42537 FlyBaseID:FBgn0004862 Length:382 Species:Drosophila melanogaster
Sequence 2:NP_055175.2 Gene:NKX2-8 / 26257 HGNCID:16364 Length:239 Species:Homo sapiens


Alignment Length:244 Identity:81/244 - (33%)
Similarity:100/244 - (40%) Gaps:83/244 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    82 KEIQPSARQPSNYLQYYAAAMDNNNHHHQATGTSNSSAADYMQRKLAYFGSTLAAPLDMRRCTSN 146
            :|.:|.|.||..    .||.:|:...|:.::..|:...                           
Human    28 REPEPRAPQPDP----CAAWLDSERGHYPSSDESSLET--------------------------- 61

  Fly   147 DSDCDSPPPLSSSPSESPLSHDGSGLSRKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKS 211
                 |||..|..||..|.| .||...::|:.|..||.||..||||||.||||||.|||.::|..
Human    62 -----SPPDSSQRPSARPAS-PGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASL 120

  Fly   212 LRLTETQVKIWFQNRRYKTKRKQ-------------IQQHEAALLGASKRVPVQVLVRE------ 257
            ||||.|||||||||.|||.||.:             .:.|.|.  |..:||.|.||||:      
Human   121 LRLTPTQVKIWFQNHRYKLKRARAPGAAESPDLAASAELHAAP--GLLRRVVVPVLVRDGQPCGG 183

  Fly   258 DGSTTYAHMAA---------------------PGAGHGLDPALINIYRH 285
            .|.......||                     ||:..||.||    |:|
Human   184 GGGGEVGTAAAQEKCGAPPAAACPLPGYPAFGPGSALGLFPA----YQH 228

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
bapNP_732637.1 Homeobox 178..231 CDD:278475 37/52 (71%)
NKX2-8NP_055175.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..87 21/95 (22%)
Homeobox 87..140 CDD:278475 37/52 (71%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0842
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D450160at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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