Protein Alignment bap and VAX2

DIOPT Version :10

• Sequence 1: NP_732637.1
• Gene: bap / 42537
• FlyBaseID: FBgn0004862
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_036608.1
• Gene: VAX2 / 25806
• HGNCID: 12661
• Length: 290
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 85/288 - (29%)
• Similarity: 120/288 - (41%)
• Gaps: 71/288 - (24%)

  Fly   103 DNNNHH-HQATGTSNSSAADYMQRKLAYFGSTLAAPLDMRRCTSNDSDCDSPPPLSSSPSESPLS 166
            |...|. .:..|||.||.|          ||         |.:..||| ..|.|..:......|.
Human    37 DGGGHSPTEVAGTSASSPA----------GS---------RESGADSD-GQPGPGEADHCRRILV 81

  Fly   167 HDGSG------------LSRKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQV 219
            .|..|            |.|.||:|.:|:..|::.||..|.:.:|:.|.||:|:|:.|.|:||||
Human    82 RDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQV 146

  Fly   220 KIWFQNRRYKTKRKQIQQHE-AALLGASKRVPVQVLVR--EDGSTTYAHMAAPGAGHGLDPALIN 281
            |:||||||.|.|:.|.:..| .|...||:......::|  |.|..    ::.|.|     |:|:
Human   147 KVWFQNRRTKQKKDQSRDLEKRASSSASEAFATSNILRLLEQGRL----LSVPRA-----PSLL- 201

  Fly   282 IYRHQLQLAYGGLPLPQMQMPFPYFYPQHKVPQPIPPPTQSSSFVTASSASSS-PVPIPIPGAVR 345
                .|..:..|||            ..|:......|...|......||||:| |:|.|:|..
Human   202 ----ALTPSLPGLP------------ASHRGTSLGDPRNSSPRLNPLSSASASPPLPPPLPAV-- 248

  Fly   346 PQRTPCPSPNGQMMSVESGAESVHSAAE 373
                 |.| :..::.:.:|.|...||.|
Human   249 -----CFS-SAPLLDLPAGYELGSSAFE 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeodomain	176..232	CDD:459649	28/55 (51%)
VAX2	NP_036608.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..75		16/57 (28%)
		Homeodomain	103..159	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	205..240		11/46 (24%)