DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bap and Vax1

DIOPT Version :9

Sequence 1:	NP_732637.1	Gene:	bap / 42537	FlyBaseID:	FBgn0004862	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_033527.1	Gene:	Vax1 / 22326	MGIID:	1277163	Length:	338	Species:	Mus musculus

Alignment Length:	299	Identity:	76/299 - (25%)
Similarity:	116/299 - (38%)	Gaps:	72/299 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 AAAMDNNNH--HHQATGTSNSSAADYMQRKLAYFGSTLAAPLDMRRCTSNDSDCDSPPPLSSSPS 161
            ||.:..|.|  ..:..|...|..|.:::.....|..:.|:           .||:..   .|:.|
Mouse    18 AARVSKNAHKESREIKGAEGSLPAAFLKEPQGAFSGSGAS-----------EDCNKS---KSNSS 68

  Fly   162 ESP------LSHDGSG------------LSRKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEM 208
            ..|      |..|..|            |.|.||:|.:|:..|::.||..|.:.:|:.|.||:|:
Mouse    69 ADPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTEL 133

  Fly   209 AKSLRLTETQVKIWFQNRRYKTKRKQIQQHEAALLGASKRVPVQVL-VREDGSTTYAHMAAPGAG 272
            |:.|.|:|||||:||||||.|.|:.|.:..|...:.:.......|| :.|.|..    ::.||..
Mouse   134 ARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLLEQGRL----LSPPGLP 194

  Fly   273 HGLDPALINIYRHQLQLAYGGLPLPQMQMPFPYFYPQHKVPQPIPPPTQSSSFVTASSASSSPVP 337
            ..|.|....    .|..|..|..||                 .:.....:.|...|::|:::..|
Mouse   195 ALLPPCATG----ALGSALRGPSLP-----------------ALGAGAAAGSAAAAAAAAAATAP 238

  Fly   338 IPIPGAVRPQ----RTPCPSPNGQMMSVESGAESVHSAA 372
            .|...|.:.|    ..|.|.|        :|...:|:.|
Mouse   239 GPAGAASQHQPAVGGAPGPGP--------AGPGGLHAGA 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeobox	178..231	CDD:278475	26/52 (50%)
Vax1	NP_033527.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..69		12/64 (19%)
		Homeobox	103..156	CDD:306543	26/52 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	239..269		8/37 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	318..338
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910