Protein Alignment bap and Nkx2-1

DIOPT Version :10

• Sequence 1: NP_732637.1
• Gene: bap / 42537
• FlyBaseID: FBgn0004862
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_001390509.1
• Gene: Nkx2-1 / 21869
• MGIID: 108067
• Length: 423
• Species: Mus musculus
• Alignment Length: 323
• Identity: 89/323 - (27%)
• Similarity: 119/323 - (36%)
• Gaps: 112/323 - (34%)

  Fly    16 LSKSLTTPFSINDILTRSNPETRRMSSVDSEPEPEKLKPSSDRERSISKSPPLCCRDLGLYKLTQ 80
            :|...|||||::|||:                      |..:..:.:..........|..|:
Mouse    54 MSPKHTTPFSVSDILS----------------------PLEESYKKVGMEGGGLGAPLAAYR--- 93

  Fly    81 PKEIQPSARQPSNYLQYYAAAMDNNNHHHQATGTSNSSAADYMQRKLAYFGSTLAAPLDMRRCTS 145
                |..|..|:..:|.:|.     .||...|...:.:||...|...:..|.         .|..
Mouse    94 ----QGQAAPPAAAMQQHAV-----GHHGAVTAAYHMTAAGVPQLSHSAVGG---------YCNG 140

  Fly   146 NDSDCDSPPPLSSS-------------------PSESPLSHDGSGLS------------------ 173
            |..:....||...:                   |:.|......||::
Mouse   141 NLGNMSELPPYQDTMRNSASGPGWYGANPDPRFPAISRFMGPASGMNMSGMGGLGSLGDVSKNMA 205

  Fly   174 ------RKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKR 232
                  |:|| |..||.|||:||||||.||:|||.|||..:|..:.||.|||||||||.|||.||
Mouse   206 PLPSAPRRKR-RVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKR 269

  Fly   233 --------KQIQ----------------QHEAALLGASKRVPVQVLVREDGSTTYAHMAAPGA 271
                    :|:|                |.:.|...:.:||.|.|||: ||....|...||||
Mouse   270 QAKDKAAQQQLQQDSGGGGGGGGGAGCPQQQQAQQQSPRRVAVPVLVK-DGKPCQAGAPAPGA 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeodomain	176..232	CDD:459649	37/55 (67%)
Nkx2-1	NP_001390509.1	Homeodomain	213..269	CDD:459649	37/56 (66%)