DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bap and EN2

DIOPT Version :9

Sequence 1:	NP_732637.1	Gene:	bap / 42537	FlyBaseID:	FBgn0004862	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_001418.2	Gene:	EN2 / 2020	HGNCID:	3343	Length:	333	Species:	Homo sapiens

Alignment Length:	91	Identity:	36/91 - (39%)
Similarity:	48/91 - (52%)	Gaps:	9/91 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   143 CTSNDSDCDSPPPLSSSP-SESPLSHDGSGLSRKKRSRAAFSHAQVFELERRFAQQRYLSGPERS 206
            || ..||..|..|.|..| .::|...|       ||.|.||:..|:..|:..|...|||:...|.
Human   219 CT-RYSDRPSSGPRSRKPKKKNPNKED-------KRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQ 275

  Fly   207 EMAKSLRLTETQVKIWFQNRRYKTKR 232
            .:|:.|.|.|:|:||||||:|.|.|:
Human   276 SLAQELSLNESQIKIWFQNKRAKIKK 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeobox	178..231	CDD:278475	23/52 (44%)
EN2	NP_001418.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..49
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	95..206
		homeobox domain	243..302		27/66 (41%)
		Homeobox	247..300	CDD:306543	23/52 (44%)
		Engrail_1_C_sig	302..331	CDD:313702	36/91 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910