Protein Alignment bap and NKX2-3

DIOPT Version :9

• Sequence 1: NP_732637.1
• Gene: bap / 42537
• FlyBaseID: FBgn0004862
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_660328.2
• Gene: NKX2-3 / 159296
• HGNCID: 7836
• Length: 364
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 91/294 - (30%)
• Similarity: 128/294 - (43%)
• Gaps: 74/294 - (25%)

  Fly    21 TTPFSINDILTRSNPETRRMSSVDSEPEPEKLKPSSDRERSISKSPPLCCRDLGLYKLTQPKEIQ 85
            :||||:.|||   |.|.:......:..:       :|.|.....:|.:.....|.......:|.:
Human     9 STPFSVKDIL---NLEQQHQHFHGAHLQ-------ADLEHHFHSAPCMLAAAEGTQFSDGGEEDE 63

  Fly    86 PSARQPSNYLQYYAAAMDNNNHHHQATGTSNSSAADYMQRKLAYFGSTLAAPLD----------- 139
            ....:..:||...|||   :.|     |.|......|:...|.   .:.:.|.:
Human    64 EDEGEKLSYLNSLAAA---DGH-----GDSGLCPQGYVHTVLR---DSCSEPKEHEEEPEVVRDR 117

  Fly   140 ------MRRCTSNDSDCDSPPPLSSSPSESPLSHDGSGLSRKKRSRAAFSHAQVFELERRFAQQR 198
                  :::......||.     ::..||.|...     ||:| .|..||.||||||||||.|||
Human   118 SQKSCQLKKSLETAGDCK-----AAEESERPKPR-----SRRK-PRVLFSQAQVFELERRFKQQR 171

  Fly   199 YLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQIQQHEAALLGA------SKRVPVQVLVRE 257
            |||.|||..:|.||:||.|||||||||||||.||:  :|.::..|||      .:||.|.||||:
Human   172 YLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQ--RQDKSLELGAHAPPPPPRRVAVPVLVRD 234

  Fly   258 D-----------------GSTTYAHMAAPGAGHG 274
            .                 |::.|::.:.|..|:|
Human   235 GKPCVTPSAQAYGAPYSVGASAYSYNSFPAYGYG 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeobox	178..231	CDD:278475	40/52 (77%)
NKX2-3	NP_660328.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	132..153		8/31 (26%)
		HOX	148..204	CDD:197696	42/56 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810