DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bap and Hoxd3

DIOPT Version :9

Sequence 1:	NP_732637.1	Gene:	bap / 42537	FlyBaseID:	FBgn0004862	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_034598.2	Gene:	Hoxd3 / 15434	MGIID:	96207	Length:	433	Species:	Mus musculus

Alignment Length:	352	Identity:	92/352 - (26%)
Similarity:	130/352 - (36%)	Gaps:	78/352 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 VDSEPEPEKLKPSSDRERSISKSPPLCCRDLGLYKLTQPKEIQPSARQPSNYLQYYAAAMDNNNH 107
            ::||.:|.:..|           ||             |..:.||:  |:|......|.....
Mouse   110 LNSEQQPPQPPP-----------PP-------------PPTLPPSS--PTNPGSGVPAKKTKG-- 146

  Fly   108 HHQATGTSNSSAADYMQRKL-AYFGSTLAAPLDMRRCTSNDSDC-DSPPPLSSSPSESPLSHDGS 170
                 |.|.||::..:.::: .:...:.........|.::..:| |..||       .|.|
Mouse   147 -----GLSASSSSSTISKQIFPWMKESRQNSKQKNSCATSGENCEDKSPP-------GPAS---- 195

  Fly   171 GLSRKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQI 235
                 ||.|.|::.||:.|||:.|...|||..|.|.|||..|.|||.|:||||||||.|.|:.|.
Mouse   196 -----KRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 255

  Fly   236 QQ---HEAALLGASKRVPVQVLVREDGSTTYAHMAAPGAGHGLD----PALINIYRHQLQLAYGG 293
            .:   |..|.....:..|   |....|...|:....|..|...|    ||......:...||...
Mouse   256 AKGILHSPAGQSPERSPP---LGGAAGHVAYSGQLPPVPGLAYDAPSPPAFAKSQPNMYGLAAYT 317

  Fly   294 LPL-----PQMQMPFPYFYPQHKVPQPIPPPTQSSSFVTASSASSSPVPIPIPGAVRPQRTPCPS 353
            .||     .|.:.|.|.|       :|.|..:....|.:|:...|   |:.:.|.......|...
Mouse   318 APLSSCLPQQKRYPAPEF-------EPHPMASNGGGFASANLQGS---PVYVGGNFVDSMAPTSG 372

  Fly   354 P--NGQMMSVESGAESVHSAAEDVDEN 378
            |  |...:|..|.|...:|.|..:..|
Mouse   373 PVFNLGHLSHPSSASVDYSCAAQIPGN 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeobox	178..231	CDD:278475	30/52 (58%)
Hoxd3	NP_034598.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	44..198		24/136 (18%)
		Antp-type hexapeptide	161..166		0/4 (0%)
		Homeobox	199..251	CDD:278475	30/51 (59%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	258..280		4/24 (17%)
		DUF4074	370..431	CDD:290032	8/30 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	401..433
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910