DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bap and AgaP_AGAP003671

DIOPT Version :9

Sequence 1:	NP_732637.1	Gene:	bap / 42537	FlyBaseID:	FBgn0004862	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	XP_313453.5	Gene:	AgaP_AGAP003671 / 1274346	VectorBaseID:	AGAP003671	Length:	485	Species:	Anopheles gambiae

Alignment Length:	521	Identity:	203/521 - (38%)
Similarity:	239/521 - (45%)	Gaps:	192/521 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 AGLSKSL-TTPFSINDILTRSNPETRRMSSVDSEPEPE--------------------------- 50
            |..:||: :||||||||||||....|..|...|..|.:
Mosquito     5 ASTAKSIVSTPFSINDILTRSRRVERHSSGESSGNEEDMQTFYHPRHHHNHYHAQHTRHTQHVRR 69

  Fly    51 -KLKPSSDRERSISKSPPLCCRDLGLY-KLTQPKEIQPSARQPSNYLQYYAAAMDNNNHHHQATG 113
             .|:||.....::.:         ||| ||:               :.||    :|||:::.||.
Mosquito    70 GTLEPSGSPRSTVEE---------GLYGKLS---------------MSYY----NNNNNNNNATT 106

  Fly   114 TS--------------------------------------------------------------- 115
            .|
Mosquito   107 PSGFPVNGLPPALRRGSLDCFMVSAEPVREHGEDVAARPDTGDGGGDGGNPSERIASMLLEGARP 171

  Fly   116 --NSSAADYMQRKLAYFGSTLAAPLDMRRCTSNDSDCDSPPPLSSSPSESPLS-HDGSGL----- 172
              :.:|..|...|.|:..|  .:|:||||...|||||||.|    ||....|. |.|...
Mosquito   172 SASVTATCYRLSKAAHQRS--ESPIDMRRLAENDSDCDSSP----SPYTGSLGLHGGQATTLHTS 230

  Fly   173 -----SRKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKR 232
                 :||||||||||||||||||||||||||||||||||:||:|||||||||||||||||||||
Mosquito   231 EEMPSARKKRSRAAFSHAQVFELERRFAQQRYLSGPERSELAKNLRLTETQVKIWFQNRRYKTKR 295

  Fly   233 KQIQQHEAALLGASKRVPVQVLVREDGSTTYAHMAAPGAGH---GLDPALINIYRHQLQLAYG-- 292
            |||||||||||.|:||||||||||||||  |..|.|.|..|   ||||||:|:||||:|:|||
Mosquito   296 KQIQQHEAALLSATKRVPVQVLVREDGS--YGPMLAAGQPHYATGLDPALLNVYRHQIQMAYGMP 358

  Fly   293 GLPLPQMQMPFPYFYPQH--KVPQ-PIPP------PTQSSSFVTAS------------SASSSPV 336
            |:|    .|||.||||..  .||. ||.|      |:.|||..:.|            :|||.|:
Mosquito   359 GIP----SMPFSYFYPSKMATVPNGPIAPSVVLSAPSSSSSSSSNSCKPPSSHHGPLQAASSGPL 419

  Fly   337 -----------PIPIPGAVRPQRTPCPSPNG----QMMSVE-SGAESVHSAA----EDVDENVEI 381
                       .:...|...|.....|..:.    ..|.|: ||..||.|:|    ||..|||||
Mosquito   420 NFSTRCDSDAENVNSTGRRSPSELSGPGSDDVRSRSRMDVDVSGHCSVLSSAGEGDEDECENVEI 484

  Fly   382 D 382
            |
Mosquito   485 D 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeobox	178..231	CDD:278475	50/52 (96%)
AgaP_AGAP003671	XP_313453.5	HOX	238..294	CDD:197696	53/55 (96%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	114	1.000	Domainoid score	I11898
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	276	1.000	Inparanoid score	I5340
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D858478at2759
OrthoFinder	1	1.000	-	-		FOG0003099
OrthoInspector	1	1.000	-	-		oto110172
Panther	1	1.100	-	-	LDO	PTHR24340
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4759
TreeFam	1	0.960	-	-
	11	10.930