DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bap and AgaP_AGAP000779

DIOPT Version :9

Sequence 1:	NP_732637.1	Gene:	bap / 42537	FlyBaseID:	FBgn0004862	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	XP_311317.5	Gene:	AgaP_AGAP000779 / 1272369	VectorBaseID:	AGAP000779	Length:	1114	Species:	Anopheles gambiae

Alignment Length:	413	Identity:	83/413 - (20%)
Similarity:	123/413 - (29%)	Gaps:	137/413 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 KSLTTPFSINDILT------RSNPETRRMSSVDSEPE---------PEKLKPSSDRERSISKSPP 67
            :|...|.|..|::|      :.||..|  ..:|.|.|         .||::.......:.|:..|
Mosquito   538 ESARRPASSIDVVTMPEGVAQQNPSER--MEIDEEEEEHEEDESCAEEKVEVVMGSSTAGSRQSP 600

  Fly    68 LCCRDLGLYKLTQPKEIQPSARQPSNYLQYYAAAMDNNNHHHQATGTSNSSAADYMQRKLAYFGS 132
            ....:..|.|:|                       ||.:    |....|...:.:..:|..|
Mosquito   601 AAFHEEALQKIT-----------------------DNGS----AVEEQNGEESSHQPQKSEY--- 635

  Fly   133 TLAAPLDMRRCTSNDSDCDSPPPLSSSPSESPLSHDGSGLSRKKRSRAAFSHAQVFELERRFAQQ 197
                       .......:|...|...|.:.||  |...:..|.|.|.:.|..|..||::.:|:.
Mosquito   636 -----------PEEQQSAESKLILPLLPKQEPL--DEPAMDGKVRVRTSISEEQQNELKKYYARN 687

  Fly   198 RYLSGPERSE---MAKSLRLTETQVKIWFQNRRYKTKRKQIQQHEAALLGASKRVPVQVLVREDG 259
               |.|.|.|   :|:.:::....|::||||.|.:       :.:..:.|.|..|.|.......|
Mosquito   688 ---SKPSRDEFQAIAQHVKMEARVVQVWFQNNRSR-------ERKMGVTGGSGGVGVGRQYAAGG 742

  Fly   260 STTYAHMAAPG-------------------------------------AGHGLDPALINIYRHQL 287
            ........||.                                     .|..|..|..|......
Mosquito   743 GQAGGQTVAPAGTPNSPLHADRAPSVVTGQDATGDQPLDLSVKKGLLTVGEALLSAATNSQAAAT 807

  Fly   288 QLAYGGLPLPQMQ-------------------MPFPYFYPQHKVPQPIPPPT---QSSSFVTASS 330
            .||.|.||...:|                   .|..|||  |.: .||...|   |:.:.:...:
Mosquito   808 ALAAGSLPAVLLQADTMSALNEAINLSIKASCSPTAYFY--HDI-HPIHGVTAGPQAHAMLGLGT 869

  Fly   331 ASSSPVPIPIPGAVRPQRTPCPS 353
            ......|.|..|  |.|.|..||
Mosquito   870 GLPRDTPSPQDG--RGQHTAAPS 890

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeobox	178..231	CDD:278475	17/55 (31%)
AgaP_AGAP000779	XP_311317.5	C2H2 Zn finger	197..217	CDD:275368
		C2H2 Zn finger	228..248	CDD:275368
		zf-H2C2_2	241..267	CDD:290200
		COG5048	250..>303	CDD:227381
		zf-C2H2	257..279	CDD:278523
		C2H2 Zn finger	259..279	CDD:275368
		zf-H2C2_2	271..296	CDD:290200
		C2H2 Zn finger	287..304	CDD:275368
		Homeobox	669..721	CDD:278475	17/61 (28%)
		zf-C2H2	1025..1047	CDD:278523
		C2H2 Zn finger	1027..1047	CDD:275368
		zf-H2C2_2	1039..1064	CDD:290200
		COG5048	1050..>1103	CDD:227381
		C2H2 Zn finger	1055..1075	CDD:275368
		zf-H2C2_2	1067..1092	CDD:290200
		C2H2 Zn finger	1083..1100	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910