DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bap and Hoxa3

DIOPT Version :9

Sequence 1:	NP_732637.1	Gene:	bap / 42537	FlyBaseID:	FBgn0004862	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_001300749.1	Gene:	Hoxa3 / 103690130	RGDID:	1561431	Length:	444	Species:	Rattus norvegicus

Alignment Length:	307	Identity:	79/307 - (25%)
Similarity:	109/307 - (35%)	Gaps:	104/307 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 PEPEKLKP-----SSDRERSISKSPPLCCRDLGLYKLTQPKEIQPSARQPSNYLQYYAAAMDNNN 106
            |.|..:.|     |:....|.:|||.|....:|       |:|.|..::            ...|
  Rat   121 PPPSSVSPPQSANSNPTPASTAKSPLLNSPTVG-------KQIFPWMKE------------SRQN 166

  Fly   107 HHHQATGTSNSSAADYMQRKLAYFGSTLAAPLDMRRCTSNDSDCDSPPPLSSSPSESPLSHDGSG 171
            ...:.:|:|:..:                       |..     |..||               |
  Rat   167 TKQKTSGSSSGES-----------------------CAG-----DKSPP---------------G 188

  Fly   172 LSRKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQIQ 236
            .:..||:|.|::.||:.|||:.|...|||..|.|.|||..|.|||.|:||||||||.|.|:.|..
  Rat   189 QASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKG 253

  Fly   237 QHEAALLGASKRVPVQVLVREDGSTTYAHMAAPGAGHGLDP--ALINIYRHQLQLAYGGLPLPQM 299
            :              .:|....|.:.......||||..|:.  :|:|...::          ||.
  Rat   254 K--------------GMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYE----------PQS 294

  Fly   300 QMPF------PYFYPQHKVPQPI-----PPPTQSSSFVTASSASSSP 335
            ..||      .|..|....|.|:     |||.|.......|.|..:|
  Rat   295 PPPFSKPPQGAYGLPPASYPAPLPSCAPPPPPQKRYTAAGSGAGGTP 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeobox	178..231	CDD:278475	30/52 (58%)
Hoxa3	NP_001300749.1	COG5576	<182..309	CDD:227863	52/170 (31%)
		Homeobox	196..249	CDD:395001	30/52 (58%)
		DUF4074	379..442	CDD:404218
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910