DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bap and hoxc10

DIOPT Version :9

Sequence 1:	NP_732637.1	Gene:	bap / 42537	FlyBaseID:	FBgn0004862	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_001258236.1	Gene:	hoxc10 / 100487723	XenbaseID:	XB-GENE-486915	Length:	351	Species:	Xenopus tropicalis

Alignment Length:	218	Identity:	64/218 - (29%)
Similarity:	100/218 - (45%)	Gaps:	38/218 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 PETRRMSSVDSEPEPEKLKPSSDRERSISKSPPLCCRDLGLYKLTQPKEIQPSARQPSNYLQYYA 99
            ||||  ||....|.|...:.|  :..|:.|:|  .|...|.::.|.......|||  |..|:...
Frog   135 PETR--SSDHEVPVPSYYRAS--QGYSMEKTP--SCHTTGDFETTFENRTSVSAR--SEILEQQQ 191

  Fly   100 AA-----MDNNNHHHQATG----TSNSSAADYMQRKLAYFGSTLAAPL------DMRRCTSNDSD 149
            |.     .:|....:|:..    ||:::|:|....|      :|.||.      |.....:.|:.
Frog   192 AGGKGGFPENTKTDNQSLATNLTTSSATASDIKTEK------SLPAPKLPPSEGDKEPSKNTDTS 250

  Fly   150 CDSPPPLSSSPSESPLSHD---GSGLSRK--KRSRAAFSHAQVFELERRFAQQRYLSGPERSEMA 209
            .|:    |.:.::..:..:   |:.|:.|  ::.|..::..|..|||:.|....||:...|.|::
Frog   251 TDN----SDAEAKEDIKAENAAGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEIS 311

  Fly   210 KSLRLTETQVKIWFQNRRYKTKR 232
            ||:.||:.||||||||||.|.|:
Frog   312 KSINLTDRQVKIWFQNRRMKLKK 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeobox	178..231	CDD:278475	25/52 (48%)
hoxc10	NP_001258236.1	COG5576	227..>340	CDD:227863	37/118 (31%)
hoxc10	NP_001258236.1	Homeobox	280..334	CDD:365835	25/53 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910