DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bap and shox

DIOPT Version :9

Sequence 1:	NP_732637.1	Gene:	bap / 42537	FlyBaseID:	FBgn0004862	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	XP_004911874.1	Gene:	shox / 100486480	XenbaseID:	XB-GENE-920752	Length:	334	Species:	Xenopus tropicalis

Alignment Length:	248	Identity:	67/248 - (27%)
Similarity:	98/248 - (39%)	Gaps:	58/248 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 TGTSN--------SSAADYMQRKLAYFGSTLAAPLDMRRCTSNDSDCDSPPPLSSSPSESPLSHD 168
            |.|||        ...||..:.||..:|||..:. .:..|.....|..|.            ..|
Frog    98 TDTSNHCPLHLYKEHGADSDKDKLKDYGSTRVSE-GIYECKEKRDDVKSE------------DED 149

  Fly   169 GSGLSRKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRK 233
            |....:::|||..|:..|:.||||.|.:..|.....|.|:::.|.|:|.:|::||||||.|.:::
Frog   150 GQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQ 214

  Fly   234 QIQQHE---AALLGASKRVPVQVLVREDGSTTYAHMAAPGAGHGLDPALINIYRHQLQLAYGGLP 295
            :.|.|:   ..:||.             ||.......||....|   ||    |...|.....|.
Frog   215 ENQMHKGGYGVILGT-------------GSHLETCRVAPYVNMG---AL----RMPFQQVQAQLQ 259

  Fly   296 LPQMQMPFPYFYPQHKVPQP---IPPP-----------TQSSSFVTASSASSS 334
            |..:....|:.:|......|   .|||           |.|::.|.|::|.|:
Frog   260 LEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLADTASAAAVVAAAAKSN 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeobox	178..231	CDD:278475	23/52 (44%)
shox	XP_004911874.1	Homeobox	159..213	CDD:365835	23/53 (43%)
shox	XP_004911874.1	OAR	314..330	CDD:367680
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910