DRSC/TRiP Functional Genomics Resources

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Protein Alignment tin and nkx2.1

DIOPT Version :9

Sequence 1:NP_524433.1 Gene:tin / 42536 FlyBaseID:FBgn0004110 Length:416 Species:Drosophila melanogaster
Sequence 2:NP_571851.1 Gene:nkx2.1 / 81883 ZFINID:ZDB-GENE-010404-1 Length:346 Species:Danio rerio


Alignment Length:388 Identity:99/388 - (25%)
Similarity:137/388 - (35%) Gaps:162/388 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly    34 NTTPFSVKDILNMVNQTEAYEGSYGHIDGAATASALFAAGEYQNPHQYLNHQQHQQSELPIPQQQ 98
            :||||||.|||:.:.::.......|:..||..||       |:.|.              :.|  
Zfish     7 HTTPFSVSDILSPLEESYKKVSMEGNNLGAPLAS-------YRQPQ--------------VTQ-- 48

  Fly    99 LHHQHLDDGATTSSSLSPLLPPPPHQLYGGYQDYGMPAHMFQHHHGH----PHQSFQHSASAYNM 159
                                                 |.|.|||.||    |        :||:|
Zfish    49 -------------------------------------AAMQQHHMGHNGTVP--------AAYHM 68

  Fly   160 SASQFYAGASATAYQTPATYNYNYAGSGEVYGGATPSAVGIKSEYIPTPYVTPSPTLDLNSSAEV 224
            :|    ||.|..::              ...||.....:|..|: :|               |..
Zfish    69 TA----AGVSQLSH--------------TAMGGYCNGNLGNMSD-LP---------------AYQ 99

  Fly   225 DSLQAPTQKLCVNPLSQRLMETASNSSSLRSIYGSDEGAKKKDNSQVTSSRSELRKNS---ISGN 286
            |.::..|              ||:      |.||::...:....|:...|.|.:...|   :|..
Zfish   100 DGMRGST--------------TAT------SWYGTNPDPRFSTISRFMGSSSGMNMGSMSTLSSL 144

  Fly   287 SNPGSNSGSTKPRMKRKPRVLFSQAQVLELECRFRLKKYLTGAEREIIAQKLNLSATQVKIWFQN 351
            ::.|...|......:||.|||||||||.|||.||:.:|||:..|||.:|..::|:.|||||||||
Zfish   145 ADVGKGMGPLTSTPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQN 209

  Fly   352 RRYKSKRGDIDCEGIAKHLKLKSEPLDSPTSLPPPIPNHVMWPPTMQQSQQQQQHHAQQQQMQ 414
            .|||.||...|                                 .:.|.|.||.:.:.|||.|
Zfish   210 HRYKMKRQAKD---------------------------------KVSQQQMQQDNGSCQQQQQ 239

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tinNP_524433.1 HOX 301..357 CDD:197696 36/55 (65%)
nkx2.1NP_571851.1 Homeobox 162..215 CDD:278475 34/52 (65%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0842
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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