Protein Alignment tin and NKX2-4

DIOPT Version :9

• Sequence 1: NP_524433.1
• Gene: tin / 42536
• FlyBaseID: FBgn0004110
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_149416.1
• Gene: NKX2-4 / 644524
• HGNCID: 7837
• Length: 354
• Species: Homo sapiens
• Alignment Length: 382
• Identity: 108/382 - (28%)
• Similarity: 154/382 - (40%)
• Gaps: 111/382 - (29%)

  Fly    34 NTTPFSVKDILNMVNQTEAYEGSYGHIDGA--ATASALFAAGEYQNPHQYLNHQQHQQSELPIPQ 96
            :||||||.|||:.:.:|  |:...|.:|||  ...:.|.||..|:.|.             |.|.
Human     7 HTTPFSVSDILSPIEET--YKKFSGAMDGAPPGLGAPLGAAAAYRAPP-------------PGPS 56

  Fly    97 QQLHHQHLDDGATTSSSLSPLLPPPPHQLYGGYQDYGMPAHMFQHHHGHPHQSFQHSASAYNMSA 161
            .|         |.|.:.:.     |.|.:.|                        |:|:| ..:|
Human    57 SQ---------AATVAGMQ-----PSHAMAG------------------------HNAAA-AAAA 82

  Fly   162 SQFYAGASATAYQTPATYNYNYAGSGEVYGGATPSAVGIKSEYIPTPYVTPSPTLDLNSSAEVDS 226
            :...|.|:||.:..|....:.:...|....|    .:|...| :|               |..|.
Human    83 AAAAAAAAATYHMPPGVSQFPHGAMGSYCNG----GLGNMGE-LP---------------AYTDG 127

  Fly   227 LQ--APTQKLCVNP------LSQRLMETAS-NSSSLRSIYGSDEGAKKKDNSQVTSSRSELRKNS 282
            ::  |.|.....||      :|:.:..:|. |.:.:.|:.|..:.||         |...|.
Human   128 MRGGAATGWYGANPDPRYSSISRFMGPSAGVNVAGMGSLTGIADAAK---------SLGPLH--- 180

  Fly   283 ISGNSNPGSNSGSTKPRMKRKPRVLFSQAQVLELECRFRLKKYLTGAEREIIAQKLNLSATQVKI 347
                    :.:.:..||.||  |||||||||.|||.||:.:|||:..|||.:|..::|:.|||||
Human   181 --------AAAAAAAPRRKR--RVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKI 235

  Fly   348 WFQNRRYKSKRGDIDCEGIAKHLKLKSEPLDSPTSLPPPIPNHVMWPPTMQQSQQQQ 404
            ||||.|||.||...|    ....:|:.|....|...|||.|..|..|..::..:..|
Human   236 WFQNHRYKMKRQAKD----KAAQQLQQEGGLGPPPPPPPSPRRVAVPVLVKDGKPCQ 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tin	NP_524433.1	HOX	301..357	CDD:197696	36/55 (65%)
NKX2-4	NP_149416.1	Homeobox	192..245	CDD:278475	35/54 (65%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	246..329		12/47 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810