Protein Alignment tin and en1b

DIOPT Version :10

• Sequence 1: NP_524433.1
• Gene: tin / 42536
• FlyBaseID: FBgn0004110
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_001013516.1
• Gene: en1b / 541371
• ZFINID: ZDB-GENE-980526-6
• Length: 274
• Species: Danio rerio
• Alignment Length: 317
• Identity: 72/317 - (22%)
• Similarity: 111/317 - (35%)
• Gaps: 97/317 - (30%)

  Fly    97 QQLHHQHLDDGATTSSSLSPLLPPPPHQLYGGYQDYGMPAHMFQHHHGHPHQSFQHSASAYNMSA 161
            :|......|...:.|.||||.:|.||..                     |||:.|.:....|...
Zfish     3 EQKDQNSRDSTESESVSLSPNIPSPPIL---------------------PHQAAQQAHRTTNFFI 46

  Fly   162 SQFYA--------GASATAYQTPATYNYNYAGSGEVYGGATPSAVGIKSEYIPTPYVTPSPTLDL 218
            .....        ..|....||....|.|            |..:        .|....|...|.
Zfish    47 DNILRPDFGCKKDPGSRDRAQTSGRENVN------------PMVI--------RPSHNSSLCQDS 91

  Fly   219 NSSAEVDSLQAPTQKLCVNPLSQRLMETASNSSSLRSIYGSDEGAKKKDNSQVTSSRSELRKNSI 283
            |.|::..|             |......:|..||::...|:  |:....|.:.|.|...:..|
Zfish    92 NCSSDSTS-------------SSSSSSPSSKQSSVKHFEGN--GSTAARNGENTPSIMMVNAN-- 139

  Fly   284 SGNSNPG-----------------SNSGSTKPRMK-----------RKPRVLFSQAQVLELECRF 320
             |.:.|.                 |:..|:.||.:           ::||..|:..|:..|:..|
Zfish   140 -GGTPPAKESQPLLWPAWVYCTRYSDRPSSGPRTRKLKKKKSEKEDKRPRTAFTAEQLQRLKAEF 203

  Fly   321 RLKKYLTGAEREIIAQKLNLSATQVKIWFQNRRYKSKRGDIDCEGIAKHLKLKSEPL 377
            :..:|:|...|:.:||:|||:.:|:||||||:|.|.|:......|:|  |:|.::.|
Zfish   204 QANRYITEQRRQSLAQELNLNESQIKIWFQNKRAKIKKASGYKNGLA--LQLMAQGL 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tin	NP_524433.1	Homeodomain	302..358	CDD:459649	23/55 (42%)
en1b	NP_001013516.1	Homeodomain	186..241	CDD:459649	23/54 (43%)
		Engrail_1_C_sig	242..272	CDD:431338	5/19 (26%)