Protein Alignment tin and nkx2.2b

DIOPT Version :10

• Sequence 1: NP_524433.1
• Gene: tin / 42536
• FlyBaseID: FBgn0004110
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_001007783.2
• Gene: nkx2.2b / 493627
• ZFINID: ZDB-GENE-050217-3
• Length: 237
• Species: Danio rerio
• Alignment Length: 195
• Identity: 62/195 - (31%)
• Similarity: 87/195 - (44%)
• Gaps: 46/195 - (23%)

  Fly   260 DEGAKKKDNSQVTSSRSELRKNSISGNS-----------NPGSNSGSTKPR-------MKRKPRV 306
            |||.......|..|||..|...|..|:.           ||..::..:..|       .|||.|:
Zfish    36 DEGLNANQKKQHDSSRDALWLGSSCGHKYPVPSASPEELNPELSADESVDRESSEDSGKKRKRRI 100

  Fly   307 LFSQAQVLELECRFRLKKYLTGAEREIIAQKLNLSATQVKIWFQNRRYKSKRGDIDCEGIAKHLK 371
            |||:.|..|||.|||.::||:..|||.:|:.|:|:.|||||||||.|||.||...: :|:..:|.
Zfish   101 LFSKTQTFELERRFRQQRYLSAPEREHLAKLLHLTPTQVKIWFQNHRYKVKRARAE-KGLDPYLL 164

  Fly   372 LKSEPLDSPTSLPPPI------PNHVMWPPTMQQS--------------QQQQQHHAQQQQMQHM 416
                   ||..:..|:      |.|::.|..:..|              ...|.||:....:.|:
Zfish   165 -------SPRRVSIPVLVRDGRPCHLLGPQDITASIPPATAPFTAFNMKPFPQIHHSHNNIVTHL 222

  Fly   417  416
            Zfish   223  222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tin	NP_524433.1	Homeodomain	302..358	CDD:459649	33/55 (60%)
nkx2.2b	NP_001007783.2	Homeodomain	96..152	CDD:459649	33/55 (60%)