Protein Alignment tin and NKX2-2

DIOPT Version :9

• Sequence 1: NP_524433.1
• Gene: tin / 42536
• FlyBaseID: FBgn0004110
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_002500.1
• Gene: NKX2-2 / 4821
• HGNCID: 7835
• Length: 273
• Species: Homo sapiens
• Alignment Length: 230
• Identity: 76/230 - (33%)
• Similarity: 106/230 - (46%)
• Gaps: 44/230 - (19%)

  Fly   206 PTPYVTPSPTLDLNSSAEVDSLQA-----PTQKLCVNPLSQRLMETASNSSSLRSIYGSDEGAKK 265
            |.|.....|   |...| :|::|:     |......||.::.|   ||......|::|...||..
Human    39 PEPAKRAGP---LGQGA-LDAVQSLPLKNPFYDSSDNPYTRWL---ASTEGLQYSLHGLAAGAPP 96

  Fly   266 KDNSQVTSSRSELRKNSISGNSNPGSNSGSTKPRMKRKPRVLFSQAQVLELECRFRLKKYLTGAE 330
            :|:|. .|......::..:....||....:.|   |||.|||||:||..|||.|||.::||:..|
Human    97 QDSSS-KSPEPSADESPDNDKETPGGGGDAGK---KRKRRVLFSKAQTYELERRFRQQRYLSAPE 157

  Fly   331 REIIAQKLNLSATQVKIWFQNRRYKSKRGDIDCEGIAKHLKLKSEPLDSPTSLPPPI------PN 389
            ||.:|..:.|:.|||||||||.|||.||...: :|      ::..||.||..:..|:      |.
Human   158 REHLASLIRLTPTQVKIWFQNHRYKMKRARAE-KG------MEVTPLPSPRRVAVPVLVRDGKPC 215

  Fly   390 HV-----MWPPTMQ----------QSQQQQQHHAQ 409
            |.     :...|.|          ||.|..|::||
Human   216 HALKAQDLAAATFQAGIPFSAYSAQSLQHMQYNAQ 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tin	NP_524433.1	HOX	301..357	CDD:197696	35/55 (64%)
NKX2-2	NP_002500.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..56		6/20 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	90..131		10/44 (23%)
		Homeobox	131..185	CDD:395001	32/53 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.810