DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tin and vnd

DIOPT Version :9

Sequence 1:	NP_524433.1	Gene:	tin / 42536	FlyBaseID:	FBgn0004110	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_476786.2	Gene:	vnd / 31003	FlyBaseID:	FBgn0261930	Length:	723	Species:	Drosophila melanogaster

Alignment Length:	460	Identity:	132/460 - (28%)
Similarity:	186/460 - (40%)	Gaps:	132/460 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LQHHQQQAQSGGYYDHYTQSPSPGSLTNADALNTTPFSVKDILNMVNQTEAYEGSYGHIDGAATA 66
            |.||.....:.|   |..|    ||.|:..||:.||..       |:..|.:.|| |...||..|
  Fly   230 LSHHSASESTSG---HRGQ----GSHTSPSALSPTPAG-------VSADEHHNGS-GTGGGAGEA 279

  Fly    67 SALFAAGEYQNP-----HQYLNHQQHQQSELPIPQQQLHHQHLDDGATTSSSLSPLLPPPPHQLY 126
            .. .:..|:..|     .|:.:||||....|.:|||  |||         .:::||  |..|...
  Fly   280 DH-HSTTEHHAPPSHPQQQHPHHQQHHHPHLLLPQQ--HHQ---------QAVAPL--PLAHHQS 330

  Fly   127 GGYQDYGMPAHMFQHHHGHPHQSFQHSASAYNMSASQFYA----------------GASATAYQT 175
            |..|.           |.|.:.:..|..:::|.:|:...|                |...::|..
  Fly   331 GEAQS-----------HAHANAAAAHLLASHNAAAAAAVAAGQYLPNLPKNFPGSFGDEMSSYHH 384

  Fly   176 PATYNYNYAG------SGEVYGGATP----SAVGIKSE----YIPTPYVTPSPTL--DLNS---S 221
            .|.....::|      ..|:||...|    |...:.||    ||.:...| ||.|  |..|   |
  Fly   385 MAQTMLQHSGRSAWIKENELYGTQQPASPDSTSPVTSEVSYTYIGSNCQT-SPALSGDYKSYSRS 448

  Fly   222 AEVDSLQ-------------------APTQKLCVNPLSQRLMETASNSSSLRS--IYGSDEGAKK 265
            |:.|:|.                   |||.....|..:.   .|.:|:.||::  |.|:..|
  Fly   449 ADSDALSVGDALHTLHGSSGNGSAGGAPTAHALHNNNNN---TTNNNNHSLKAEGINGAGSG--- 507

  Fly   266 KDNSQVTSSRSELRKNSI----------SGNSNPGSNSGSTKPRMKRKPRVLFSQAQVLELECRF 320
            .|:|        |.::.|          .|:....:|.....|..|||.||||::||..|||.||
  Fly   508 HDDS--------LNEDGIEEDIDDVDDADGSGGGDANGSDGLPNKKRKRRVLFTKAQTYELERRF 564

  Fly   321 RLKKYLTGAEREIIAQKLNLSATQVKIWFQNRRYKSKRGDIDCEGIAKHLKL----KSEPLDSPT 381
            |.::||:..|||.:|..:.|:.|||||||||.|||:||...: :|...|..|    .:.| ..|:
  Fly   565 RQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKTKRAQNE-KGYEGHPGLLHGHATHP-HHPS 627

  Fly   382 SLPPP 386
            :||.|
  Fly   628 ALPSP 632

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tin	NP_524433.1	HOX	301..357	CDD:197696	34/55 (62%)
vnd	NP_476786.2	Homeobox	548..601	CDD:278475	31/52 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	53	1.000	Domainoid score	I4196
eggNOG	1	0.900	-	-		E2759_KOG0842
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24340
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.910