Protein Alignment tin and nkx2.2a

DIOPT Version :10

• Sequence 1: NP_524433.1
• Gene: tin / 42536
• FlyBaseID: FBgn0004110
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_571497.2
• Gene: nkx2.2a / 30697
• ZFINID: ZDB-GENE-980526-403
• Length: 273
• Species: Danio rerio
• Alignment Length: 231
• Identity: 80/231 - (34%)
• Similarity: 107/231 - (46%)
• Gaps: 43/231 - (18%)

  Fly   202 SEYIPTPYVTPSPTLDLNSSAEVDSLQAPTQKLCVNPLSQRLMETASNSSSLRSIYGSDEGAKKK 266
            ||...||.|.....|:   :.:...|:.|......||.::.|..|.|...||..:         .
Zfish    42 SEATKTPGVLVQSPLE---NVQNLPLKNPFYDNSDNPYTRWLATTDSIQYSLHGL---------S 94

  Fly   267 DNSQVTSSRS------ELRKNSISGNSNPGSNSGSTKPRMKRKPRVLFSQAQVLELECRFRLKKY 325
            .|||.||::|      |...|....:|| ||:||.     |||.|||||:||..|||.|||.::|
Zfish    95 ANSQDTSAKSPEPSADESPDNDKETSSN-GSDSGK-----KRKRRVLFSKAQTYELERRFRQQRY 153

  Fly   326 LTGAEREIIAQKLNLSATQVKIWFQNRRYKSKRGDIDCEGIAKHLKLKSEPLDSPTSLPPPI--- 387
            |:..|||.:|..:.|:.|||||||||.|||.||...:     |.:::...|  ||..:..|:
Zfish   154 LSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAE-----KGMEVTHLP--SPRRVAVPVLVR 211

  Fly   388 ---PNHVM----WPPTMQQSQQQQQHHAQQQQMQHM 416
               |.|.:    ...|.|.......:.|  |.:|||
Zfish   212 DGKPCHTLKAQDLAATFQAGIPFSAYSA--QSLQHM 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tin	NP_524433.1	Homeodomain	302..358	CDD:459649	34/55 (62%)
nkx2.2a	NP_571497.2	COG5576	93..218	CDD:227863	57/146 (39%)
		Homeodomain	130..186	CDD:459649	34/55 (62%)