Protein Alignment tin and Tlx3

DIOPT Version :10

• Sequence 1: NP_524433.1
• Gene: tin / 42536
• FlyBaseID: FBgn0004110
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: XP_036012630.1
• Gene: Tlx3 / 27140
• MGIID: 1351209
• Length: 338
• Species: Mus musculus
• Alignment Length: 280
• Identity: 76/280 - (27%)
• Similarity: 106/280 - (37%)
• Gaps: 66/280 - (23%)

  Fly   105 DDGATTSSSLSPLLPPPPHQLYGGYQDYGMPAHMFQHHHGHPHQ--SF----------QHSASAY 157
            |..|:..|...|..||...          .||   .....|||:  ||          |.||.|.
Mouse    31 DPAASPPSPAQPFRPPRME----------APA---SAQTPHPHEPISFGIDQILNSPDQDSAPAP 82

  Fly   158 NMSASQFY-----AGASATAYQT-PATY-----NYNYAGSGEVYGGATPSAVGIKSEYIPTPYVT 211
            .......|     .|....||.: ||::     .:..|||..|.....|:.|.....:.|.|...
Mouse    83 RGPDGASYLGGPPGGRPGAAYPSLPASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAV 147

  Fly   212 PSPTLDLNSSAEVDSLQAPTQKLCVNPLSQRLMETASNSSSLRSI-YGSDEGAKK--KDNSQVTS 273
            |.|.                      |.:...|.:....|||..: :...|.:::  ||.....:
Mouse   148 PPPL----------------------PSALPAMPSVPTVSSLGGLNFPWMESSRRFVKDRFTAAA 190

  Fly   274 SRSELRKNSISGNSNPGSNSGSTKPRMKRKPRVLFSQAQVLELECRFRLKKYLTGAEREIIAQKL 338
            :.:........|  :|..|  .|.|: ::|||..||:.|:.|||.||..:|||..|||..:|:.|
Mouse   191 ALTPFTVTRRIG--HPYQN--RTPPK-RKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSL 250

  Fly   339 NLSATQVKIWFQNRRYKSKR 358
            .::..|||.||||||.|.:|
Mouse   251 KMTDAQVKTWFQNRRTKWRR 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tin	NP_524433.1	Homeodomain	302..358	CDD:459649	29/55 (53%)
Tlx3	XP_036012630.1	PRK07764	<20..>109	CDD:236090	22/90 (24%)
		Homeodomain	214..270	CDD:459649	29/55 (53%)