Protein Alignment tin and Nkx2-4

DIOPT Version :9

• Sequence 1: NP_524433.1
• Gene: tin / 42536
• FlyBaseID: FBgn0004110
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_075993.1
• Gene: Nkx2-4 / 228731
• MGIID: 97349
• Length: 354
• Species: Mus musculus
• Alignment Length: 419
• Identity: 107/419 - (25%)
• Similarity: 154/419 - (36%)
• Gaps: 146/419 - (34%)

  Fly    34 NTTPFSVKDILNMVNQTEAYEGSYGHIDGAATA-SALFAAGEYQNPHQYLNHQQHQQSELPIPQQ 97
            :||||||.|||:.:.:|  |:...|.:|||... .|...|..|:.|
Mouse     7 HTTPFSVSDILSPIEET--YKKFGGVMDGAPPGLGAPLGAAAYRAP------------------- 50

  Fly    98 QLHHQHLDDGATTSSSLSPLLPPPPHQLYGGYQDYGMPAHMFQHHHGHPHQSFQHSASAYNMSAS 162
                   ..|.::.::.......|||.:.|                        |:|:| ..:|:
Mouse    51 -------PSGPSSQAAAVAAGMQPPHAMAG------------------------HNAAA-AAAAA 83

  Fly   163 QFYAGASATAYQTPATYNYNYAGSGE------------------VYGGATPSAVGIKSEYIPTPY 209
            ...|.|:||.:..|....:.::..|.                  :.|||..:|.|
Mouse    84 AAAAAAAATYHMPPGVSQFPHSAMGSYCNGGLGNMGELPAYTDGMRGGAAAAATG---------- 138

  Fly   210 VTPSPTLDLNSSAEVDSLQAPTQKLCVNPLSQRLMETAS--NSSSLRSIYGSDEGAKKKDNSQVT 272
                 ....|:.....|:             .|.|..::  |.:.:.|:.|..:.||
Mouse   139 -----WYGANTDPRYSSI-------------SRFMGPSAGVNVAGMGSLTGIADAAK-------- 177

  Fly   273 SSRSELRKNSISGNSNPGSNSGSTKPRMKRKPRVLFSQAQVLELECRFRLKKYLTGAEREIIAQK 337
             |.:.|.               :..||.||  |||||||||.|||.||:.:|||:..|||.:|..
Mouse   178 -SLAPLH---------------AAAPRRKR--RVLFSQAQVYELERRFKQQKYLSAPEREHLASM 224

  Fly   338 LNLSATQVKIWFQNRRYKSKRGDIDCEGIAKHLKLKSEPLDSPTSLPPPIPNHVMWP-------- 394
            ::|:.|||||||||.|||.||...|  ..|:.|: :...|..|...|||.|..|..|
Mouse   225 IHLTPTQVKIWFQNHRYKMKRQAKD--KAAQQLQ-QEGGLGPPPPPPPPSPRRVAVPVLVKDGKP 286

  Fly   395 -------PTMQQSQQQQQHHAQQQQMQHM 416
                   ||..|..||.|......:::.:
Mouse   287 CQNGAGTPTPGQGGQQPQAPTPAPELEEL 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tin	NP_524433.1	HOX	301..357	CDD:197696	36/55 (65%)
Nkx2-4	NP_075993.1	Homeobox	191..244	CDD:278475	35/54 (65%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	245..329		18/74 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810