Protein Alignment tin and Nkx2-1

DIOPT Version :9

• Sequence 1: NP_524433.1
• Gene: tin / 42536
• FlyBaseID: FBgn0004110
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: XP_011242403.1
• Gene: Nkx2-1 / 21869
• MGIID: 108067
• Length: 423
• Species: Mus musculus
• Alignment Length: 454
• Identity: 109/454 - (24%)
• Similarity: 148/454 - (32%)
• Gaps: 205/454 - (45%)

  Fly    17 HYTQSP-SPGSLTNADALNTTPFSVKDILNMVNQTEAYEGSYGHIDGAATASALFAAGEYQNPHQ 80
            |.|:|. |...:.:....:||||||.|||:.:.::....|..|...||..|:
Mouse    40 HPTRSALSRRRIMSMSPKHTTPFSVSDILSPLEESYKKVGMEGGGLGAPLAA------------- 91

  Fly    81 YLNHQQHQQSELPIPQQQLHHQHLDDGATTSSSLSPLLPPPPHQLYGGYQDYGMPAHMFQHHHGH 145
               ::|.|.:                              ||            .|.|.||..||
Mouse    92 ---YRQGQAA------------------------------PP------------AAAMQQHAVGH 111

  Fly   146 PHQSFQHSA--SAYNMSASQFYAGASATAYQTPATYNYNYAGSGEVYGGATPSAVGIKSEYIPTP 208
                  |.|  :||:|:|    ||....::              ...||.....:|..|| :| |
Mouse   112 ------HGAVTAAYHMTA----AGVPQLSH--------------SAVGGYCNGNLGNMSE-LP-P 150

  Fly   209 YVTPSPTLDLNSSAEVDSLQAPTQKLCVNPLSQRLMETASNSSSLRSIYGSDEGAKKKDNSQVTS 273
            |                                  .:|..||:|....||::...:....|:...
Mouse   151 Y----------------------------------QDTMRNSASGPGWYGANPDPRFPAISRFMG 181

  Fly   274 SRSELRKNSISGNSNPGSNSGSTKP---RMKRKPRVLFSQAQVLELECRFRLKKYLTGAEREIIA 335
            ..|.:..:.:.|..:.|..|.:..|   ..:||.|||||||||.|||.||:.:|||:..|||.:|
Mouse   182 PASGMNMSGMGGLGSLGDVSKNMAPLPSAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLA 246

  Fly   336 QKLNLSATQVKIWFQNRRYKSKR----------------------GDIDCEGIAKHLKLKSEPLD 378
            ..::|:.|||||||||.|||.||                      |...|
Mouse   247 SMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQQLQQDSGGGGGGGGGAGC--------------- 296

  Fly   379 SPTSLPPPIPNHVMWPPTMQQSQQQQ----------------------------QHHAQQQQMQ 414
                            |..||:|||.                            |.|||||..|
Mouse   297 ----------------PQQQQAQQQSPRRVAVPVLVKDGKPCQAGAPAPGAASLQSHAQQQAQQ 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tin	NP_524433.1	HOX	301..357	CDD:197696	36/55 (65%)
Nkx2-1	XP_011242403.1	Homeobox	215..269	CDD:395001	34/53 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810