Protein Alignment tin and Nkx2-5

DIOPT Version :9

• Sequence 1: NP_524433.1
• Gene: tin / 42536
• FlyBaseID: FBgn0004110
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_032726.1
• Gene: Nkx2-5 / 18091
• MGIID: 97350
• Length: 318
• Species: Mus musculus
• Alignment Length: 374
• Identity: 94/374 - (25%)
• Similarity: 120/374 - (32%)
• Gaps: 175/374 - (46%)

  Fly    22 PSPGSLTNADALNTTPFSVKDILNMVNQTEAYEGSYGHIDG-----AATASALFAAGE---YQNP 78
            |||       ||..||||||||||:..|..:.  :.|.:..     .|.||.:.||.:   |..|
Mouse     3 PSP-------ALTPTPFSVKDILNLEQQQRSL--ASGDLSARLEATLAPASCMLAAFKPEAYSGP 58

  Fly    79 HQYLNHQQHQQSEL-PIPQQQLHHQHLDDGATTSSSLSPLLPPPPHQLYGGYQDYGMPAHMFQHH 142
            ....:.....::|: |.|              :....||..|..|
Mouse    59 EAAASGLAELRAEMGPAP--------------SPPKCSPAFPAAP-------------------- 89

  Fly   143 HGHPHQSFQHSASAYNMSASQFYAGASATAYQTPATYNYNYAGSGEVYGGATPSAVGIKSEYIPT 207
                                .||.||
Mouse    90 --------------------TFYPGA--------------------------------------- 95

  Fly   208 PYVTPSPTLDLNSSAEVDSLQAPTQKLCVNPLSQRLMETASNSSSLRSIYGSDEGAKKKDNSQVT 272
             |..|.|..|         .:|..::||                                   ..
Mouse    96 -YGDPDPAKD---------PRADKKELC-----------------------------------AL 115

  Fly   273 SSRSELRKNSISGNSNPGSNSGSTKPRMKRKPRVLFSQAQVLELECRFRLKKYLTGAEREIIAQK 337
            ....||.|....|...|       :.|.:||||||||||||.|||.||:.::||:..||:.:|..
Mouse   116 QKAVELDKAETDGAERP-------RARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASV 173

  Fly   338 LNLSATQVKIWFQNRRYKSKRGDIDCEGIAKHLKLKSEPLDSPTSLPPP 386
            |.|::|||||||||||||.||...|     :.|:|...|       |||
Mouse   174 LKLTSTQVKIWFQNRRYKCKRQRQD-----QTLELLGPP-------PPP 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tin	NP_524433.1	HOX	301..357	CDD:197696	37/55 (67%)
Nkx2-5	NP_032726.1	Homeobox	144..194	CDD:365835	31/49 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	115	1.000	Inparanoid score	I4814
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24340
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.920