Protein Alignment tin and Nkx2-2

DIOPT Version :9

• Sequence 1: NP_524433.1
• Gene: tin / 42536
• FlyBaseID: FBgn0004110
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_035049.1
• Gene: Nkx2-2 / 18088
• MGIID: 97347
• Length: 273
• Species: Mus musculus
• Alignment Length: 248
• Identity: 79/248 - (31%)
• Similarity: 109/248 - (43%)
• Gaps: 48/248 - (19%)

  Fly   187 GEVYGGATPSAVGIKSEYIPTPYVTPSP----TLDLNSSAEVDSLQAPTQKLCVNPLSQRLMETA 247
            |.|..|....:.|      |.|.....|    .||...|.   .|::|......||.::.|   |
Mouse    26 GSVAEGPEEESEG------PEPAKRAGPLGQGALDAVQSL---PLKSPFYDSSDNPYTRWL---A 78

  Fly   248 SNSSSLRSIYGSDEGAKKKDNSQVTSSRSELRKNSISGNSNPGSNSGSTKPRMKRKPRVLFSQAQ 312
            |......|::|....|..:|    :||:|.......|.:::..:..|......|||.|||||:||
Mouse    79 STEGLQYSLHGLAASAPPQD----SSSKSPEPSADESPDNDKETQGGGGDAGKKRKRRVLFSKAQ 139

  Fly   313 VLELECRFRLKKYLTGAEREIIAQKLNLSATQVKIWFQNRRYKSKRGDIDCEGIAKHLKLKSEPL 377
            ..|||.|||.::||:..|||.:|..:.|:.|||||||||.|||.||...: :|      ::..||
Mouse   140 TYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAE-KG------MEVTPL 197

  Fly   378 DSPTSLPPPI------PNHV-----MWPPTMQ----------QSQQQQQHHAQ 409
            .||..:..|:      |.|.     :...|.|          ||.|..|::||
Mouse   198 PSPRRVAVPVLVRDGKPCHALKAQDLAAATFQAGIPFSAYSAQSLQHMQYNAQ 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tin	NP_524433.1	HOX	301..357	CDD:197696	35/55 (64%)
Nkx2-2	NP_035049.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..56		9/35 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..131		9/43 (21%)
		Homeobox	131..185	CDD:395001	32/53 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	115	1.000	Inparanoid score	I4814
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.860