DRSC/TRiP Functional Genomics Resources

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Protein Alignment tin and Nkx3-2

DIOPT Version :9

Sequence 1:NP_524433.1 Gene:tin / 42536 FlyBaseID:FBgn0004110 Length:416 Species:Drosophila melanogaster
Sequence 2:NP_031550.2 Gene:Nkx3-2 / 12020 MGIID:108015 Length:333 Species:Mus musculus


Alignment Length:289 Identity:80/289 - (27%)
Similarity:115/289 - (39%) Gaps:80/289 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   167 GASATAYQTPATYNYNYAGSGE--VYGGA----------TPSAVGIKSEYIPTPYVTPSPTLDLN 219
            |........||...:...|..|  ..|||          |.:|||..:| .|..:.:.|...:.|
Mouse    38 GTEVAVTAAPAVCCWRIFGETEAGALGGAEDSLLASPARTRTAVGQSAE-SPGGWDSDSALSEEN 101

  Fly   220 SSAEVDSLQAPTQKLCVNPLSQRLMETASNSSSLRSIYGSDE------GAKKKDNSQVTSSRSEL 278
            ..          ::.|.:      :..||.:...|...|.|:      .||..:......|.||:
Mouse   102 EG----------RRRCAD------VPGASGTGRARVTLGLDQPGCELHAAKDLEEEAPVRSDSEM 150

  Fly   279 RKNSISGNSNP-----------------------GSNSG------------STKPRMKRKPRVLF 308
             ..|:||:.:|                       |::.|            :.|||.||. |..|
Mouse   151 -SASVSGDHSPRGEDDSVSPGGARVPGLRGAAGSGASGGQAGGVEEEEEPAAPKPRKKRS-RAAF 213

  Fly   309 SQAQVLELECRFRLKKYLTGAEREIIAQKLNLSATQVKIWFQNRRYKSKRGDIDCEGI-----AK 368
            |.|||.|||.||..::||:|.||..:|..|.|:.|||||||||||||:||..:..:.:     ||
Mouse   214 SHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRRQMAADLLASAPAAK 278

  Fly   369 HLKLKSEPLDSPTSLPPPIPNHVMWPPTM 397
            .:.:|....|.....   :|..|:.||::
Mouse   279 KVAVKVLVRDDQRQY---LPGEVLRPPSL 304

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tinNP_524433.1 HOX 301..357 CDD:197696 34/55 (62%)
Nkx3-2NP_031550.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 74..121 11/63 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 137..212 15/76 (20%)
Homeobox 209..262 CDD:278475 32/53 (60%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0842
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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