Protein Alignment tin and nkx2-3

DIOPT Version :10

• Sequence 1: NP_524433.1
• Gene: tin / 42536
• FlyBaseID: FBgn0004110
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: XP_002937234.1
• Gene: nkx2-3 / 100486189
• XenbaseID: XB-GENE-852996
• Length: 328
• Species: Xenopus tropicalis
• Alignment Length: 381
• Identity: 102/381 - (26%)
• Similarity: 131/381 - (34%)
• Gaps: 166/381 - (43%)

  Fly    22 PSPGSLTNADALNTTPFSVKDILNMVNQTEAYEGSYGHIDGAATASALFAAGEYQNPHQYLNHQQ 86
            |||        :.:||||||||||:
 Frog     4 PSP--------VTSTPFSVKDILNL---------------------------------------- 20

  Fly    87 HQQSELPIPQQQLHHQHLDDGATTSSSLSPLLPPPPHQLYGGYQDYGMPAHMFQHHHGHPHQSFQ 151
            .||.:.||    .|.|||....:.:                              |..||.|...
 Frog    21 EQQGQPPI----AHPQHLQQQCSRA------------------------------HPAHPAQDLD 51

  Fly   152 HSASAYNMSASQFYAGASATAYQTPATYNYNYAGSGE-------VYGGATPSA-VGIKSEYIPTP 208
               |.:..::....||....           ||| ||       ..|.|.|.. ||:.    |..
 Frog    52 ---SDFQQASCMLAAGERCV-----------YAG-GEDKLPFLSAMGAAEPHGDVGLS----PDR 97

  Fly   209 YVTPSPTLDLNSSAEVDSLQAPTQKLCVNPLSQRLMETASNSSSLRSIYGSDEGAKKKDNSQVTS 273
            ||               :|:.|.:            |......|||      ||.    |.....
 Frog    98 YV---------------ALRDPKE------------EDEEEEDSLR------EGG----NKSCFL 125

  Fly   274 SRSELRKNSISGNSNPGSNSGSTKPRMKRKPRVLFSQAQVLELECRFRLKKYLTGAEREIIAQKL 338
            ::|...:..:.....|       |.|.:||||||||||||.|||.||:.::||:..|||.:|..|
 Frog   126 NKSPDGEGKLEDPDRP-------KQRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLANSL 183

  Fly   339 NLSATQVKIWFQNRRYKSKRGDIDCEGIAKHLKLKSEPLDSPTSLPPPIPNHVMWP 394
            .|::|||||||||||||.||            :.:.:.|:..|..||| |..|..|
 Frog   184 KLTSTQVKIWFQNRRYKCKR------------QRQDKSLEMGTHHPPP-PRRVAVP 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tin	NP_524433.1	Homeodomain	302..358	CDD:459649	38/55 (69%)
nkx2-3	XP_002937234.1	Homeodomain	147..203	CDD:459649	38/55 (69%)