Protein Alignment SIFaR and npy2rl

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001314731.1
• Gene: npy2rl / 795311
• ZFINID: ZDB-GENE-111115-4
• Length: 373
• Species: Danio rerio
• Alignment Length: 409
• Identity: 120/409 - (29%)
• Similarity: 187/409 - (45%)
• Gaps: 75/409 - (18%)

  Fly   138 GSLAGKSLAIA-DATSSTYYSNLLNLSPATTSLISAAAATKSYNDSALRWEQLDGSVDFGFDPLY 201
            ||...|.|:|. |::..|....||.|..:|
Zfish     9 GSSGSKDLSIGEDSSDLTLNHPLLELGDST----------------------------------- 38

  Fly   202 RHSLAMSMVYCVAYIVVFLVGLIGNSFVIAVVLRAPRMRTVTNYFIVNLAIADILVIVFCLPATL 266
             ..|.:.:|..:||..:.|:|::|||.||.||.:...:|||||:||.|||:||:||...|||.||
Zfish    39 -KLLGVQVVLILAYSTIILLGVVGNSLVIYVVYKFKTLRTVTNFFIANLAVADLLVNTLCLPFTL 102

  Fly   267 IGNIFVPWMLGWLMCKFVPYIQGVSVAASVYSLIAVSLDRFIAIWWPL-KQMTKRRARIMIIGIW 330
            ...:...|..|.::|..:||.||::|..|..:|..::|||...|.:.| .:|:|....::|...|
Zfish   103 AYTLLREWKFGQVLCFTLPYAQGLAVHVSTITLNVIALDRHRCIVYHLDTRMSKDTCFLVIAITW 167

  Fly   331 VIALVTTIPWLLF-----FDLVPAEEVFSDALVSAYSQPQFLCQEVWP-PGTDGNLYFLLANLVA 389
            |::.|...|..:|     .||.|...:             .:|.|.|| ..||..|| .::.|:.
Zfish   168 VVSAVLASPLAIFREYGIVDLSPDNSI-------------EVCGEKWPDSSTDSTLY-SISTLLL 218

  Fly   390 CYLLPMSLITLCYVLIWIKVSTRSIPGESKDAQMDRMQQKSKVKVIKMLVAVVILFVLSWLPLYV 454
            .|:||:::|:..|:.||.|:.....|....|....|.      |..||||.:|::|.:||||.:.
Zfish   219 QYVLPLAIISFAYIRIWSKLRNHVSPVGRNDRHHRRR------KTTKMLVTMVVVFAVSWLPFHA 277

  Fly   455 IFARIKFG-SDISQEEFEILKKVMPVAQWLGSSNSCINPILYS-VNKKYRRGFAAIIKSRSCCGR 517
            ....|... |.:..::|.:|..|..:   :...::..||:||. :|:.||..|.|:.:   |..|
Zfish   278 FQLAIDIDHSVLDMKDFRLLYTVFHI---VAMCSTFANPLLYGWMNRNYRSAFVAVFR---CKER 336

  Fly   518 LRYYDNVAIASSTTSTRKS 536
            |   |::.......:|.:|
Zfish   337 L---DSLHTEGQPAATVRS 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	100/304 (33%)
		TM helix 1	210..236	CDD:320124	12/25 (48%)
		TM helix 2	243..269	CDD:320124	16/25 (64%)
		TM helix 3	281..311	CDD:320124	11/29 (38%)
		TM helix 4	322..340	CDD:320124	4/17 (24%)
		TM helix 5	379..404	CDD:320124	8/24 (33%)
		TM helix 6	429..459	CDD:320124	11/29 (38%)
		TM helix 7	474..498	CDD:320124	5/24 (21%)
npy2rl	NP_001314731.1	7tm_GPCRs	45..327	CDD:475119	100/304 (33%)
		TM helix 1	47..71	CDD:410628	11/23 (48%)
		TM helix 2	80..102	CDD:410628	13/21 (62%)
		TM helix 3	118..140	CDD:410628	7/21 (33%)
		TM helix 4	161..177	CDD:410628	4/15 (27%)
		TM helix 5	209..232	CDD:410628	7/23 (30%)
		TM helix 6	258..280	CDD:410628	10/21 (48%)
		TM helix 7	295..320	CDD:410628	6/27 (22%)