Protein Alignment SIFaR and npy1r

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001095861.1
• Gene: npy1r / 793668
• ZFINID: ZDB-GENE-080221-1
• Length: 380
• Species: Danio rerio
• Alignment Length: 384
• Identity: 109/384 - (28%)
• Similarity: 182/384 - (47%)
• Gaps: 37/384 - (9%)

  Fly   160 LNLSPATTSLISAAAATKSYNDSALRWEQLDGSVDFGFDPLYRHSLAMSMVYCVAYIVVFLVGLI 224
            |:||..:.:.:||.|    |.|...      ||          |||.:.|  .|||..|.|:|:|
Zfish    20 LDLSNCSITNLSAIA----YGDECY------GS----------HSLFVIM--AVAYSAVVLLGVI 62

  Fly   225 GNSFVIAVVLRAPRMRTVTNYFIVNLAIADILVIVFCLPATLIGNIFVPWMLGWLMCKFVPYIQG 289
            ||..:|.|:.|...:..|||..|.||:::|:|:.|.|||.|.|......|:.|.:|||....:|.
Zfish    63 GNLALILVIARQRELHNVTNVLIANLSVSDLLMAVVCLPFTFIYTFMDHWVFGAVMCKLNSLVQC 127

  Fly   290 VSVAASVYSLIAVSLDRFIAI-----WWPLKQMTKRRARIMIIGIWVIALVTTIPWLLFFDLVPA 349
            .||:.|::||:.::::|...|     |.|    :...|.:.|...|.:|::|..|:|||..:..|
Zfish   128 CSVSVSIFSLVLIAIERHQLILHPRGWRP----SLNHACLGISLTWALAVLTATPFLLFSRVTDA 188

  Fly   350 EEVFSDALVSAYSQPQFLCQEVWPPGTDGNLYFLLANLVACYLLPMSLITLCYVLIWIKVSTRSI 414
            ......::.....:.:.:|.|.| |..:..|.:....||..|:.|::.|.:||:.|:.::..|:.
Zfish   189 PLKQLPSVFQEQYRGKVVCVEEW-PSREIKLTYTTGMLVLQYITPLTFIFICYLKIYTRLQRRNN 252

  Fly   415 PGESKDAQMDRMQQKSKVKVIKMLVAVVILFVLSWLPLYVIFARIKFGSDISQEEFEILKKVMPV 479
            ..|.......|..:..::.:  ||.::|:.|.:.||||.|..|.|.:..:::......|  :..:
Zfish   253 MMERIRENKYRSSESKRINI--MLFSIVVAFAVCWLPLNVFNAVIDWNHEVAMNCTHNL--LFSL 313

  Fly   480 AQWLGSSNSCINPILYS-VNKKYRRGFAAIIKSRSCCGRLRYYDNVAIASSTTSTRKSS 537
            .......:.||||:.|. :|:.::|...|....:....|...||.||:::..|...|.|
Zfish   314 CHLTAMCSVCINPVFYGFLNRNFQRDLRAFRLCKIVSTRENEYDMVAMSTVNTDVSKMS 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	87/301 (29%)
		TM helix 1	210..236	CDD:320124	11/25 (44%)
		TM helix 2	243..269	CDD:320124	13/25 (52%)
		TM helix 3	281..311	CDD:320124	10/34 (29%)
		TM helix 4	322..340	CDD:320124	5/17 (29%)
		TM helix 5	379..404	CDD:320124	8/24 (33%)
		TM helix 6	429..459	CDD:320124	10/29 (34%)
		TM helix 7	474..498	CDD:320124	5/24 (21%)
npy1r	NP_001095861.1	7tmA_NPY1R	47..340	CDD:320517	87/303 (29%)
		TM helix 1	48..74	CDD:320517	12/27 (44%)
		TM helix 2	81..106	CDD:320517	12/24 (50%)
		TM helix 3	119..149	CDD:320517	9/29 (31%)
		TM helix 4	160..181	CDD:320517	6/20 (30%)
		TM helix 5	217..246	CDD:320517	9/28 (32%)
		TM helix 6	265..295	CDD:320517	10/31 (32%)
		TM helix 7	308..333	CDD:320517	6/26 (23%)