Protein Alignment SIFaR and gpr83.2

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001072505.1
• Gene: gpr83.2 / 779960
• XenbaseID: XB-GENE-993677
• Length: 420
• Species: Xenopus tropicalis
• Alignment Length: 423
• Identity: 122/423 - (28%)
• Similarity: 195/423 - (46%)
• Gaps: 51/423 - (12%)

  Fly   148 ADATSSTYYSNLLNLSPATTSLISAAAATKSYNDSALRWEQLDGSVDFGFDPLYR---HSLAMSM 209
            |.:.||..:|.|... |..:||.:...             .:|...||..|..|.   .|..:..
 Frog    20 AASNSSGIFSTLYGF-PNISSLFNGDL-------------NIDDIGDFENDTKYEAESQSSTVKA 70

  Fly   210 VYCVAYIVVFLVGLIGNSFVIAVVLRAPRMRTVTNYFIVNLAIADILVIVFCLPATLIGNIFVPW 274
            :..|||.|:.::.|.||..|..||::..||::.|:.||||||:|||::.:...|.||:..:...|
 Frog    71 LLIVAYSVIIVISLFGNILVCHVVIKNSRMQSATSLFIVNLAVADIMITLLNTPFTLVRFVSSTW 135

  Fly   275 MLGWLMCKFVPYIQGVSVAASVYSLIAVSLDRFIAIWWPLK-QMTKRRARIMIIGIWVIALVTTI 338
            :.|.|||....::|..||..||.:|:|::|||...|..||| :|:..:..|.||.||.:|...::
 Frog   136 VFGKLMCHVSRFVQYCSVHVSVLTLMAIALDRHQVIMHPLKPRMSTVKGIICIIVIWFMASGFSL 200

  Fly   339 PWLLFFDLVPAEEVFSDALVSAYSQPQF--LCQEVWPPGTDGNLYFLLANLVACYLLPMSLITLC 401
            |..::..|   |:.|....|.....|.|  .....|.       |..||..|..|:||:.:|::.
 Frog   201 PHAVYQKL---EQFFIGNTVRMVCLPSFPYPADLFWK-------YLDLATFVLLYVLPLIVISIT 255

  Fly   402 YVLIWIKVSTRSIPGESKDAQMDRMQQKSKVKVIKMLVAVVILFVLSWLPL--YVIFARIKFGSD 464
            |..:..|:..|:..|:....|....::|.|: .:|||:.||::|.:.|.||  |::....|..|.
 Frog   256 YTTVAKKLWLRNAIGDITMEQYYAHRRKKKM-TLKMLMLVVVVFAVCWFPLNCYLVLMSSKVISS 319

  Fly   465 ISQEEFEILKKVMPVAQWLGSSNSCINPILYS-VNKKYRRGFAAIIKSRSC-CGRLRYYDNVAIA 527
            .:...|..        .|...|::|.||.:|. :|:.:|....|::    | |.|.....:..:.
 Frog   320 NNAIYFAF--------HWFAMSSTCYNPFIYCWLNESFRSELKALL----CVCRRRSPAQSHPLQ 372

  Fly   528 SSTTSTR----KSSHYHQNSSRKSPSSKGNAVS 556
            |.:...|    ::.|:.|.||.::..|..|..|
 Frog   373 SVSPQFRHAWTENCHFKQGSSSQAAGSATNVNS 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	95/301 (32%)
		TM helix 1	210..236	CDD:320124	10/25 (40%)
		TM helix 2	243..269	CDD:320124	13/25 (52%)
		TM helix 3	281..311	CDD:320124	11/29 (38%)
		TM helix 4	322..340	CDD:320124	6/17 (35%)
		TM helix 5	379..404	CDD:320124	9/24 (38%)
		TM helix 6	429..459	CDD:320124	12/31 (39%)
		TM helix 7	474..498	CDD:320124	6/24 (25%)
gpr83.2	NP_001072505.1	7tmA_GPR83	70..353	CDD:320511	95/301 (32%)
		TM helix 1	71..97	CDD:320511	10/25 (40%)
		TM helix 2	104..129	CDD:320511	13/24 (54%)
		TM helix 3	142..172	CDD:320511	11/29 (38%)
		TM helix 4	183..204	CDD:320511	7/20 (35%)
		TM helix 5	233..262	CDD:320511	10/35 (29%)
		TM helix 6	282..312	CDD:320511	12/30 (40%)
		TM helix 7	321..346	CDD:320511	7/32 (22%)