Protein Alignment SIFaR and qrfpr

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_012820557.1
• Gene: qrfpr / 779748
• XenbaseID: XB-GENE-994316
• Length: 456
• Species: Xenopus tropicalis
• Alignment Length: 387
• Identity: 113/387 - (29%)
• Similarity: 201/387 - (51%)
• Gaps: 38/387 - (9%)

  Fly   201 YRHSLAMSMVYCVAYIVVFLVGLIGNSFVIAVVLRAPRMRTVTNYFIVNLAIADILVIVFCLPAT 265
            :|..:|. :..||   ::|::.|.|||.|:.||.|:..||||||.||.:||::|:|:..||:|.|
 Frog    76 FRTKIAF-VTICV---LIFVLALFGNSLVLYVVTRSKAMRTVTNIFICSLALSDLLIAFFCIPFT 136

  Fly   266 LIGNIFVPWMLGWLMCKFVPYIQGVSVAASVYSLIAVSLDRFIAIWWPLK---QMTKRRARIMII 327
            ::.||...|:.|...||.||::|..::...:.::..::::|...|..|||   |.|.|||..|:.
 Frog   137 MLQNISSNWLGGAFACKMVPFVQSTAIVTEILTMTCIAVERHQGIVHPLKMKWQYTNRRAFTMLG 201

  Fly   328 GIWVIALVTTIP-WLLFFDLVPAE--EVFSDALVSAYSQPQFLCQEVWPPGTDGNLY--FLLANL 387
            .:|:||.|..|| |       .|:  ||..|.|   |.:....|.|.|.......:|  |:   |
 Frog   202 IVWLIAAVVGIPMW-------HAQRLEVKYDFL---YEKQYVCCLEAWNSQVHQKIYTTFI---L 253

  Fly   388 VACYLLPMSLITLCYVLI----WIK--VSTRSIPGESKDAQMDRMQQKSKVKVIKMLVAVVILFV 446
            |..:|||::::.|.|..|    |||  |...|:......::|.::.:|.| :.|.|::.||:||.
 Frog   254 VILFLLPLTVMLLLYSKIGYELWIKKRVGDASVLQTIHGSEMSKIARKKK-RAIIMMITVVVLFA 317

  Fly   447 LSWLPLYVIFARIKFGSDISQEEFEILKKVMPVAQWLGSSNSCINPILYS-VNKKYRRGFAA--- 507
            :.|.|.:|:...|::.:..::.:...:|.:..:.|.:|..||..|||:|: :|:.:::.|.:
 Frog   318 VCWAPFHVVHMMIEYSNFENEYDDVTIKIIFAIVQIIGFFNSICNPIVYAFMNENFKKNFLSALC 382

  Fly   508 --IIKSRSCCGRLRYYDNVAIASSTTSTRKSSHYHQNSSRKSPSSKGNAVSYIYEHNSLRRH 567
              .::..|...|......:.:....:|:.:..:..:::.|::.|.....|.:..:..|.:||
 Frog   383 FCFLRDPSSPSRRPGNSGITLIQQKSSSSRRENTCEDTRREAFSEGNIEVKFFDQPVSKKRH 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	101/310 (33%)
		TM helix 1	210..236	CDD:320124	10/25 (40%)
		TM helix 2	243..269	CDD:320124	12/25 (48%)
		TM helix 3	281..311	CDD:320124	6/29 (21%)
		TM helix 4	322..340	CDD:320124	8/18 (44%)
		TM helix 5	379..404	CDD:320124	9/26 (35%)
		TM helix 6	429..459	CDD:320124	11/29 (38%)
		TM helix 7	474..498	CDD:320124	9/24 (38%)
qrfpr	XP_012820557.1	7tmA_QRFPR	80..377	CDD:320333	102/314 (32%)
		TM helix 1	81..107	CDD:320333	11/29 (38%)
		TM helix 2	114..140	CDD:320333	12/25 (48%)
		TM helix 3	152..182	CDD:320333	6/29 (21%)
		TM helix 4	195..216	CDD:320333	10/27 (37%)
		TM helix 5	245..270	CDD:320333	9/27 (33%)
		TM helix 6	300..330	CDD:320333	11/30 (37%)
		TM helix 7	345..370	CDD:320333	9/24 (38%)