Protein Alignment SIFaR and galr1a

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_696215.1
• Gene: galr1a / 567820
• ZFINID: ZDB-GENE-060503-290
• Length: 347
• Species: Danio rerio
• Alignment Length: 357
• Identity: 105/357 - (29%)
• Similarity: 186/357 - (52%)
• Gaps: 50/357 - (14%)

  Fly   208 SMVYCVAYIVVFLVGLIGNSFVIAVVL-RAP-RMRTVTNYFIVNLAIADILVIVFCLPATLIGNI 270
            ::|..:.:.::|.:|::|||.||.|:. |.| :.|:.||.||:||::||:..::||:|......:
Zfish    32 NLVTLLIFGLIFTLGVLGNSLVITVLAQRKPGQQRSTTNIFILNLSVADLSYLLFCIPFQSTVYM 96

  Fly   271 FVPWMLGWLMCKFVPYIQGVSVAASVYSLIAVSLDRFIAIWWPLKQMTKRRARIMIIG---IWVI 332
            ...|:||..:|||:.|...||:..|:::|.|:|:||:|||....|..:.|.||..:||   |||:
Zfish    97 LPTWILGAFICKFIHYFFTVSMLVSIFTLSAMSVDRYIAIVHCRKSSSIRVARHALIGVLVIWVL 161

  Fly   333 ALVTTIPWLLFFDLVPAEEVFSDALVSAYSQPQFLCQEVWPPGTDGNLYFLLANLVACYLLPMSL 397
            :.....|...:..:|.:|:            ....|.||| |..|....:::...|..|:||:.|
Zfish   162 SFAMATPVAYYQGIVESED------------NSTFCWEVW-PDHDRRKIYVVCTFVFGYVLPLIL 213

  Fly   398 ITLCY--VLIWIKVSTRSIPGESKDAQMDRMQQKSKVKVIKMLVAVVILFVLSWLPLYVIFARIK 460
            |:.||  ||..:....|::..:|         :.||.|..:.::.||::|.|||||.:|:...::
Zfish   214 ISFCYAKVLNHLHKKLRNVSKKS---------EASKKKTAQTVLVVVVVFCLSWLPHHVVHLWVE 269

  Fly   461 FGS-DISQEEFEILKKVMPVAQWLGSSNSCINPILYS-VNKKYRRGFAAIIKSRSCCGRLRYYDN 523
            ||| .::|..| :|:   ..|..|..|||.:||::|: :::.:|:.:..:.:.:
Zfish   270 FGSFPLNQASF-VLR---VAAHCLAYSNSSVNPVIYAFLSENFRQAYKQVFRCQ----------- 319

  Fly   524 VAIASSTTSTRKSSHYHQNSSRKSPSSKGNAV 555
            ||....|...|:.    ::.:..:||:....|
Zfish   320 VASECPTNEAREM----KSKTEAAPSTNCTTV 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	98/304 (32%)
		TM helix 1	210..236	CDD:320124	9/26 (35%)
		TM helix 2	243..269	CDD:320124	11/25 (44%)
		TM helix 3	281..311	CDD:320124	14/29 (48%)
		TM helix 4	322..340	CDD:320124	7/20 (35%)
		TM helix 5	379..404	CDD:320124	8/26 (31%)
		TM helix 6	429..459	CDD:320124	12/29 (41%)
		TM helix 7	474..498	CDD:320124	8/24 (33%)
galr1a	XP_696215.1	7tmA_Gal1_R	33..312	CDD:320226	98/304 (32%)
		TM helix 1	34..60	CDD:320226	9/25 (36%)
		TM helix 2	69..95	CDD:320226	11/25 (44%)
		TM helix 3	107..137	CDD:320226	14/29 (48%)
		TM helix 4	149..169	CDD:320226	6/19 (32%)
		TM helix 5	195..224	CDD:320226	10/28 (36%)
		TM helix 6	238..268	CDD:320226	12/29 (41%)
		TM helix 7	280..305	CDD:320226	10/28 (36%)