Protein Alignment SIFaR and tacr1b

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001268728.1
• Gene: tacr1b / 564017
• ZFINID: ZDB-GENE-091117-17
• Length: 412
• Species: Danio rerio
• Alignment Length: 390
• Identity: 110/390 - (28%)
• Similarity: 182/390 - (46%)
• Gaps: 52/390 - (13%)

  Fly   209 MVYCVAYIVVFLVGLIGNSFVIAVVLRAPRMRTVTNYFIVNLAIADILVIVFCLPATLIGNIFVP 273
            :::.:||..:.||.::||..||.::|...|||||||||:||||.|:..:..|......|..:...
Zfish    40 VLWAIAYCTIVLVSVVGNITVIWIILAHKRMRTVTNYFLVNLAFAEASMSAFNTVINFIYAVHNE 104

  Fly   274 WMLGWLMCKFVPYIQGVSVAASVYSLIAVSLDRFIAIWWPLKQ-MTKRRARIMIIGIWVIALVTT 337
            |..|.:.|:|..:....:|.||:||:.|::|||::||..||:| ::....::::..||.:||:..
Zfish   105 WYFGLVYCRFHNFFPIAAVFASIYSMTAIALDRYMAIIHPLQQRLSSAETKLVVCVIWALALMLA 169

  Fly   338 IPWLLFFDLVPAEEVFSDALVSAYSQPQFLCQEVWPPGT--DGNLYFLLANLVACYLLPMSLITL 400
            .|...|..             :|....:.:|...||..:  |....:.:..:|..|.||:.::..
Zfish   170 FPQYYFSS-------------TAQLPGRVVCYINWPEYSMWDFQKTYYVCVVVLIYFLPLLVMGC 221

  Fly   401 CYVLIWIKVSTRSIPGESKDAQMDRMQQKSKVKVIKMLVAVVILFVLSWLPLYVIFARIKFGSDI 465
            .|:::...:....|||:|.|..  |.|..:|.||:||::.||..|...|||.:|.|...:|...:
Zfish   222 AYLVVGCFLWASEIPGDSSDRY--REQLIAKRKVVKMMIVVVCTFATCWLPYHVYFIVHQFLPHL 284

  Fly   466 SQEEFEILKKVMPVAQWLGSSNSCINPILYS-VNKKYRRGFAAIIKSRSCCGR----------LR 519
            .:|.:  :::|.....||..|::..|||:|. :|.::|.||........|..:          .|
Zfish   285 FEERY--IQQVYLGIMWLAMSSTMYNPIIYCLLNDRFRAGFQQAFSWCPCVPQGSYEGLELKSTR 347

  Fly   520 YYDNVAI------ASSTTST--------------RKSSHYHQNSSRKSPSSKGNAVSYIYEHNSL 564
            |....|.      ..:|.||              |.|.....|.|.:| :||..:.|..|..|::
Zfish   348 YLQTQASIFRASRMETTVSTVMPTGDGELPENPNRSSVDLTSNGSSRS-ASKTVSESSFYSSNNV 411

  Fly   565  564
            Zfish   412  411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	91/299 (30%)
		TM helix 1	210..236	CDD:320124	9/25 (36%)
		TM helix 2	243..269	CDD:320124	11/25 (44%)
		TM helix 3	281..311	CDD:320124	12/29 (41%)
		TM helix 4	322..340	CDD:320124	4/17 (24%)
		TM helix 5	379..404	CDD:320124	5/24 (21%)
		TM helix 6	429..459	CDD:320124	13/29 (45%)
		TM helix 7	474..498	CDD:320124	8/24 (33%)
tacr1b	NP_001268728.1	7tm_GPCRs	40..323	CDD:475119	91/299 (30%)
		TM helix 1	42..66	CDD:410628	8/23 (35%)
		TM helix 2	75..97	CDD:410628	9/21 (43%)
		TM helix 3	113..135	CDD:410628	7/21 (33%)
		TM helix 4	156..172	CDD:410628	4/15 (27%)
		TM helix 5	201..224	CDD:410628	4/22 (18%)
		TM helix 6	254..276	CDD:410628	9/21 (43%)
		TM helix 7	291..316	CDD:410628	8/24 (33%)