Protein Alignment SIFaR and galr1b

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001314772.1
• Gene: galr1b / 561989
• ZFINID: ZDB-GENE-140624-1
• Length: 350
• Species: Danio rerio
• Alignment Length: 341
• Identity: 102/341 - (29%)
• Similarity: 177/341 - (51%)
• Gaps: 50/341 - (14%)

  Fly   213 VAYIVVFLVGLIGNSFVIAVV--LRAPRMRTVTNYFIVNLAIADILVIVFCLP--ATLIGNIFVP 273
            |.:..:|.:|:|||:.|:.|:  :::.|.|:.||.||:||:|||:..::||:|  ||:..   :|
Zfish    38 VIFGCIFFLGIIGNTLVMVVIGKIKSRRSRSTTNIFILNLSIADLSFLLFCVPFQATIYS---LP 99

  Fly   274 -WMLGWLMCKFVPYIQGVSVAASVYSLIAVSLDRFIAIWWPLKQMTKRRARIMIIG---IWVIAL 334
             |:.|..:||||.|...||:..|:::|:|:|:||:||:....|....|..|..:||   ||:::.
Zfish   100 EWIFGAFLCKFVHYFVMVSMLVSIFTLVAMSVDRYIAVVLSKKSPCIRNRRNALIGVCVIWMLSF 164

  Fly   335 VTTIPWLLFFDLVPAEEVFSDALVSAYSQPQFLCQEVWPPGTDGNLYFLLANLVACYLLPMSLIT 399
            :..:|       |...::.:|...:..|.   .|.|:|......:.| .:..||..||||:.|||
Zfish   165 IFAVP-------VAQHQILTDHPKAPNST---FCWEIWTERVAKHTY-KVTILVIGYLLPLLLIT 218

  Fly   400 LCYVLIWIKVSTRSIPGESKDAQMDRMQQKSKVKVIKMLVAVVILFVLSWLPLYVIFARIKFG-- 462
            .||..:...:       ..|...|.:..::||.|..:.::.||..|::.|:|.::|...::||
Zfish   219 CCYAKVLYHL-------HKKIKNMSKKSERSKRKTAQTVLLVVAAFLICWMPHHIIAMWVEFGQF 276

  Fly   463 --SDISQEEFEILKKVMPVAQWLGSSNSCINPILYS-VNKKYRRGFAAIIKSRSCCG-------- 516
              :|.| ..|.|      ::..|...|||:|||||: :::.:|:....:...|....
Zfish   277 PLNDAS-FAFRI------ISHCLAYGNSCVNPILYAFLSENFRKACKQVFTCRFFYSPPPVEKVV 334

  Fly   517 RLRYYDNVAIASSTTS 532
            |:| .:|.::..|||:
Zfish   335 RIR-MENFSMTHSTTN 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	95/304 (31%)
		TM helix 1	210..236	CDD:320124	8/24 (33%)
		TM helix 2	243..269	CDD:320124	14/27 (52%)
		TM helix 3	281..311	CDD:320124	15/29 (52%)
		TM helix 4	322..340	CDD:320124	5/20 (25%)
		TM helix 5	379..404	CDD:320124	12/24 (50%)
		TM helix 6	429..459	CDD:320124	9/29 (31%)
		TM helix 7	474..498	CDD:320124	9/24 (38%)
galr1b	NP_001314772.1	7tmA_Gal1_R	34..315	CDD:320226	95/304 (31%)
		TM helix 1	35..61	CDD:320226	8/22 (36%)
		TM helix 2	70..96	CDD:320226	14/25 (56%)
		TM helix 3	108..138	CDD:320226	15/29 (52%)
		TM helix 4	150..170	CDD:320226	6/26 (23%)
		TM helix 5	198..227	CDD:320226	12/29 (41%)
		TM helix 6	241..271	CDD:320226	9/29 (31%)
		TM helix 7	283..308	CDD:320226	11/30 (37%)