Protein Alignment SIFaR and tacr3l

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001243564.1
• Gene: tacr3l / 559201
• ZFINID: ZDB-GENE-061207-19
• Length: 395
• Species: Danio rerio
• Alignment Length: 394
• Identity: 114/394 - (28%)
• Similarity: 201/394 - (51%)
• Gaps: 47/394 - (11%)

  Fly   210 VYCVAYIVVFLVGLIGNSFVIAVVLRAPRMRTVTNYFIVNLAIADILVIVFCLPATLIGNIFV-- 272
            |:.|||..|..|.:.||..||.::|...|||||||||::|||.:|..:..|   .|||..|:.
Zfish    27 VWSVAYSSVLAVAVFGNLIVIWIILAHKRMRTVTNYFLLNLAFSDASMAAF---NTLINFIYATH 88

  Fly   273 -PWMLGWLMCKFVPYIQGVSVAASVYSLIAVSLDRFIAIWWPLK-QMTKRRARIMIIGIWVIALV 335
             .|..|.:.|||..:....:|.||:||:.|:::||::||..||| :::....:::|:.||.:|::
Zfish    89 GEWYFGEVYCKFHNFFPVTAVFASIYSMTAIAVDRYMAIIHPLKPRLSATATKVVIVCIWALAVI 153

  Fly   336 TTIPWLLFFDLVPAEEVFSDALVSAYSQP-QFLCQEVWP-PGTDGNLYFLLANLVACYLLPMSLI 398
            ...| |.|:.             :..:.| :.:|...|| |..|..:|.::.. |..|:||:.::
Zfish   154 LAFP-LCFYS-------------TTRTMPRRTICYVAWPRPAEDSFMYHIIVT-VLVYMLPLVVM 203

  Fly   399 TLCYVLIWIKVSTRSIPGESKDAQMDRMQQKSKVKVIKMLVAVVILFVLSWLPLYVIFARIKFGS 463
            .:.|.::.:.:....|||:|.|..:.  |.::|.||:||::.||:.|.|.|||.::.|  |..|.
Zfish   204 GITYTIVGVTLWGGEIPGDSSDNYVG--QLRAKRKVVKMMIVVVVTFALCWLPYHIYF--IVTGL 264

  Fly   464 DISQEEFEILKKVMPVAQWLGSSNSCINPILY-SVNKKYRRGFAAIIKSRSCCG--RLRYYDNVA 525
            :....:::.:::|.....||..|::..|||:| .:|.::|.||....:   .|.  ::..||.:.
Zfish   265 NKRLNKWKSIQQVYLSVLWLAMSSTMYNPIIYCCLNGRFRAGFKRAFR---WCPFIQVSSYDELE 326

  Fly   526 I----------ASSTTSTRKSSHYHQNSSRKS--PSSKGNAVSYIYEHNSLRRHNMMLKQDSNLS 578
            :          :|..|.:|..:..|....|:|  .|:|...:..:.:.|: ....:.|.:|...:
Zfish   327 LRPTRLHPRNQSSMCTLSRVDTSLHGEDPRRSQRKSTKSQCLVEVRDENT-PATKLCLNRDQAFA 390

  Fly   579 QQML 582
            .:.|
Zfish   391 TEQL 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	97/301 (32%)
		TM helix 1	210..236	CDD:320124	11/25 (44%)
		TM helix 2	243..269	CDD:320124	12/25 (48%)
		TM helix 3	281..311	CDD:320124	12/29 (41%)
		TM helix 4	322..340	CDD:320124	4/17 (24%)
		TM helix 5	379..404	CDD:320124	6/24 (25%)
		TM helix 6	429..459	CDD:320124	13/29 (45%)
		TM helix 7	474..498	CDD:320124	8/24 (33%)
tacr3l	NP_001243564.1	7tm_GPCRs	26..307	CDD:475119	97/301 (32%)
		TM helix 1	28..52	CDD:320669	9/23 (39%)
		TM helix 2	61..83	CDD:320669	11/24 (46%)
		TM helix 3	99..121	CDD:320669	8/21 (38%)
		TM helix 4	142..158	CDD:320669	5/16 (31%)
		TM helix 5	185..208	CDD:320669	5/23 (22%)
		TM helix 6	238..260	CDD:320669	10/23 (43%)
		TM helix 7	275..300	CDD:320669	8/24 (33%)