Protein Alignment SIFaR and Qrfprl

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001102709.1
• Gene: Qrfprl / 500157
• RGDID: 1560028
• Length: 415
• Species: Rattus norvegicus
• Alignment Length: 340
• Identity: 105/340 - (30%)
• Similarity: 183/340 - (53%)
• Gaps: 46/340 - (13%)

  Fly   195 FGFDPLY-------RHSLAMSMVYCVAYIVVFLVGLIGNSFVIAVVLRAPRMRTVTNYFIVNLAI 252
            :|..||.       |..||:    .:|.:::|.:.|.||:.|:.||.|:..||||||.||.:||:
  Rat    28 YGLRPLVLTPQLPARARLAL----LLAGLLIFALALFGNALVVYVVTRSKAMRTVTNIFICSLAL 88

  Fly   253 ADILVIVFCLPATLIGNIFVPWMLGWLMCKFVPYIQGVSVAASVYSLIAVSLDRFIAIWWPLK-- 315
            :|:|::.||:|.|::.|:...|:.|..:||.||::|..:|...:.::..::::|...:..|.|
  Rat    89 SDLLIVFFCIPVTMLQNVSDTWLGGAFICKMVPFVQCTAVVTEILTMTCIAVERHQGLVHPFKMK 153

  Fly   316 -QMTKRRARIMIIGIWVIALVTTIP-WLLFFDLVPAEEVFSDALVSAYSQPQFLCQEVWPPGTDG 378
             |.|.:||..|:..:|::|::...| |     .|...|:..|.|   |.:....|.|.|......
  Rat   154 QQYTNQRAFTMLGVVWLVAIIIGSPMW-----HVQRLEIKYDFL---YEKEHICCLEEWSSPVHQ 210

  Fly   379 NLY--FLLANLVACYLLPMSLITLCYVLI----WIKVST------RSIPGESKDAQMDRMQQKSK 431
            .:|  |:|..|   :|||:.|:::.|..|    |||...      |:|.|:    :|.::.:|.|
  Rat   211 KIYTTFILVTL---FLLPLLLLSVLYGKIGYELWIKKRVGDGSVLRTIHGK----EMFKIARKKK 268

  Fly   432 VKVIKMLVAVVILFVLSWLPLYVIFARIKFGSDISQEEFEI-LKKVMPVAQWLGSSNSCINPILY 495
            ..|| |:|.||:||.:.|.|.:|:...|:: |:..:|..|: :|.:..:.|.:|..||..|||:|
  Rat   269 RAVI-MMVTVVVLFAVCWAPFHVVHMMIEY-SNFEKEYDEVTIKMIFAIVQIIGFFNSICNPIVY 331

  Fly   496 S-VNKKYRRGFAAII 509
            : :|:.:::.|.:.:
  Rat   332 ALMNENFKKNFVSAV 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	98/313 (31%)
		TM helix 1	210..236	CDD:320124	8/25 (32%)
		TM helix 2	243..269	CDD:320124	12/25 (48%)
		TM helix 3	281..311	CDD:320124	7/29 (24%)
		TM helix 4	322..340	CDD:320124	5/18 (28%)
		TM helix 5	379..404	CDD:320124	9/26 (35%)
		TM helix 6	429..459	CDD:320124	13/29 (45%)
		TM helix 7	474..498	CDD:320124	9/24 (38%)
Qrfprl	NP_001102709.1	7tmA_QRFPR	60..342	CDD:320333	95/298 (32%)
		TM helix 2	79..105	CDD:320333	12/25 (48%)
		TM helix 3	117..147	CDD:320333	7/29 (24%)
		TM helix 4	160..181	CDD:320333	7/25 (28%)
		TM helix 5	210..235	CDD:320333	9/27 (33%)
		TM helix 6	265..295	CDD:320333	13/30 (43%)
		TM helix 7	310..335	CDD:320333	9/24 (38%)