Protein Alignment SIFaR and AstA-R1

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Alignment Length: 406
• Identity: 111/406 - (27%)
• Similarity: 203/406 - (50%)
• Gaps: 63/406 - (15%)

  Fly   124 LLATLAATTTASARGSLA-GKSLAIADATSSTYYSNLLNLSPATTSLISAAAATKSYNDSALRWE 187
            |||||.::...::.|:.. |..:::::::.:.|                  |.|..:.|.:  ..
  Fly    10 LLATLISSWPKASWGATGNGSIISVSNSSGNNY------------------AFTSEHTDHS--DH 54

  Fly   188 QLDGSVDFGFDPLYRHSLAMSMVYCVAYIVVFLVGLIGNSFVIAVVLRAPRMRTVTNYFIVNLAI 252
            ..:.|:::..:.:....: :|.:..|.:.::...||:||..||.||:...:||:.||..|:|||:
  Fly    55 NANDSMEYDAESVALERI-VSTIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAV 118

  Fly   253 ADILVIVFCLPATLIGNIFVPWMLGWLMCKFVPYIQGVSVAASVYSLIAVSLDRFIAIWWPLKQM 317
            :|||.::||:|.|....:...|..|.:.||||.|:..|:...|||:|:.:|.|||:|:..|:..|
  Fly   119 SDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSM 183

  Fly   318 ---TKRRARIMIIGIWVIALVTTIPWLLFFDLVPAEEVFSDALVSAYSQPQFLCQEVWPPGTDGN 379
               |:|.|.:.|:..|:..:.|.||..|... |...:...:|..:.....:   :|:|     ..
  Fly   184 SLRTERNATLAIMCAWITIVTTAIPVALSHS-VRIYQYHGNAGTACVFSTE---EEIW-----SL 239

  Fly   380 LYFLLANLVACYLLPMSLITLCYV----LIWIKVSTRSIPGESKDAQMDRMQQKSKVKVIKMLVA 440
            :.|.::..::.|:.|::||...|:    .:|     :|.||....|:    .:|.|.:|.:|:|.
  Fly   240 VGFQVSFFLSSYVAPLTLICFLYMGMLARLW-----KSAPGCKPSAE----SRKGKRRVTRMVVV 295

  Fly   441 VVILFVLSWLPLYVIFA----RIKFGSDISQEEFEILKKVMPVAQWLGSSNSCINPILYS-VNKK 500
            ||:.|.:.|||::||..    .:..||.:|    .|::.:..|..:   :|||||||||: ::..
  Fly   296 VVLAFAICWLPIHVILVLKALNLYGGSHLS----VIIQIISHVVAY---TNSCINPILYAFLSDN 353

  Fly   501 YRRGFAAIIKSRSCCG 516
            :|:.|..::    .||
  Fly   354 FRKAFRKVV----WCG 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	95/307 (31%)
		TM helix 1	210..236	CDD:320124	9/25 (36%)
		TM helix 2	243..269	CDD:320124	13/25 (52%)
		TM helix 3	281..311	CDD:320124	15/29 (52%)
		TM helix 4	322..340	CDD:320124	5/17 (29%)
		TM helix 5	379..404	CDD:320124	6/28 (21%)
		TM helix 6	429..459	CDD:320124	13/33 (39%)
		TM helix 7	474..498	CDD:320124	10/24 (42%)
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	95/307 (31%)
		TM helix 1	76..102	CDD:320224	9/25 (36%)
		TM helix 2	109..135	CDD:320224	13/25 (52%)
		TM helix 3	147..177	CDD:320224	15/29 (52%)
		TM helix 4	189..209	CDD:320224	6/19 (32%)
		TM helix 5	239..268	CDD:320224	6/28 (21%)
		TM helix 6	284..314	CDD:320224	13/29 (45%)
		TM helix 7	326..351	CDD:320224	11/27 (41%)