Protein Alignment SIFaR and NPFR

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Alignment Length: 411
• Identity: 105/411 - (25%)
• Similarity: 199/411 - (48%)
• Gaps: 60/411 - (14%)

  Fly   168 SLISAAAATKSYNDSALRWEQLD----------GSVDFGFDPLYRHSLAMSMVYCVAYIVVFLVG 222
            :|.:.|..|...|::..|  .||          .:||   .|.|...::|       |.|:.:.|
  Fly    48 ALNTTAINTSDLNETGSR--PLDPVLIDRFLSNRAVD---SPWYHMLISM-------YGVLIVFG 100

  Fly   223 LIGNSFVIAVVLRAPRMRTVTNYFIVNLAIADILVIVFCLPATLIGNIFVPWMLG--WLMCKFVP 285
            .:||:.|:..|:|.|.|||..|.||:||||:|:|:.:..:|.||:..:...|..|  .::||.:.
  Fly   101 ALGNTLVVIAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEILSKYWPYGSCSILCKTIA 165

  Fly   286 YIQGVSVAASVYSLIAVSLDRFIAIWWPLKQMTKRRARIMII-GIWVIALVTTIPWLLFFDLVPA 349
            .:|.:.:..|..|:.|::.||:..|.:|.:...:....:.|: |||.:||:...|..::.:|:..
  Fly   166 MLQALCIFVSTISITAIAFDRYQVIVYPTRDSLQFVGAVTILAGIWALALLLASPLFVYKELINT 230

  Fly   350 EEVFSDALVSAYSQPQFL--CQEVWPPGTDGNLYFLLANLVACYLLPMSLITLCYVLIWIKVSTR 412
            :   :.||:........:  |.|.| |..:|..|:.:.:|...||:|:.::::.|..|:.|:.:|
  Fly   231 D---TPALLQQIGLQDTIPYCIEDW-PSRNGRFYYSIFSLCVQYLVPILIVSVAYFGIYNKLKSR 291

  Fly   413 ----SIPGESKDAQMDRMQQKSKVKVIKMLVAVVILFVLSWLPL--YVIFARIKFGSDISQEEFE 471
                ::...|...:::|.::..:...  :|:::.|:|.:|||||  :.::|        ..|...
  Fly   292 ITVVAVQASSAQRKVERGRRMKRTNC--LLISIAIIFGVSWLPLNFFNLYA--------DMERSP 346

  Fly   472 ILKKVM---PVAQWLGSSNSCINPILYS-VNKKYRRGFAAIIKSRSCCGRLRYYD-NVAIASSTT 531
            :.:.::   .:...:|.|::|.||:||. :|..:|:.|..::     |   |..| |||:...||
  Fly   347 VTQSMLVRYAICHMIGMSSACSNPLLYGWLNDNFRKEFQELL-----C---RCSDTNVALNGHTT 403

  Fly   532 STRKSSHYHQNSSRKSPSSKG 552
            .....:...:.....:..|||
  Fly   404 GCNVQAAARRRRKLGAELSKG 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	81/310 (26%)
		TM helix 1	210..236	CDD:320124	7/25 (28%)
		TM helix 2	243..269	CDD:320124	12/25 (48%)
		TM helix 3	281..311	CDD:320124	8/29 (28%)
		TM helix 4	322..340	CDD:320124	6/18 (33%)
		TM helix 5	379..404	CDD:320124	6/24 (25%)
		TM helix 6	429..459	CDD:320124	9/31 (29%)
		TM helix 7	474..498	CDD:320124	7/27 (26%)
NPFR	NP_001246947.1	7tmA_NPYR-like	88..384	CDD:320331	82/316 (26%)
		TM helix 1	88..114	CDD:320331	8/32 (25%)
		TM helix 2	121..146	CDD:320331	12/24 (50%)
		TM helix 3	161..191	CDD:320331	8/29 (28%)
		TM helix 4	202..223	CDD:320331	7/20 (35%)
		TM helix 5	258..287	CDD:320331	7/28 (25%)
		TM helix 6	310..340	CDD:320331	8/31 (26%)
		TM helix 7	352..377	CDD:320331	7/24 (29%)