Protein Alignment SIFaR and npy8br

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_571511.1
• Gene: npy8br / 30713
• ZFINID: ZDB-GENE-980526-208
• Length: 375
• Species: Danio rerio
• Alignment Length: 400
• Identity: 122/400 - (30%)
• Similarity: 201/400 - (50%)
• Gaps: 74/400 - (18%)

  Fly   198 DPLYRHSLAMSMVYCVAYIVVFLVGLIGNSFVIAVVLRAPRMRTVTNYFIVNLAIADILVIVFCL 262
            ||....||:.:....|||..:..|||:||:.::.|:.|...||.|||.|||||:.:||||.:.||
Zfish    15 DPTCPASLSSTTFLIVAYSTMLAVGLVGNTCLVVVITRQKEMRNVTNIFIVNLSCSDILVCLVCL 79

  Fly   263 PATLIGNIFVPWMLGWLMCKFVPYIQGVSVAASVYSLIAVSLDRFIAI-----WWPLKQMTKRRA 322
            |.|:|..:...|:||..:||..|::|.:||..|::|::.::|:|...|     |.|:    .|.:
Zfish    80 PVTIIYTLMDRWILGEALCKVTPFVQCMSVTVSIFSMVLIALERHQLIIHPTGWKPV----VRHS 140

  Fly   323 RIMIIGIWVIALVTTIPWLLFFDLV--PAEEV------FSDALVSAYSQPQFLCQEVWPPGTDGN 379
            .:.:..||:||...::|:|.|..|.  |...:      |||         .|:|.|.||  ::||
Zfish   141 YLAVAVIWIIACFISLPFLSFNILTNSPFHNLSLPFNPFSD---------HFICIEQWP--SEGN 194

  Fly   380 LYFLLANLVAC-YLLPMSLITLCYVLIWIKVSTRSIPGESKDAQMDR----MQQKSK--VKVIKM 437
            .......|:.| |.||::||.:||..|::::|.|      || .::|    .|:|:|  .:|..|
Zfish   195 RLTYTTTLLLCQYCLPLALILVCYFRIFLRLSRR------KD-MVERARGGRQKKAKGSKRVNAM 252

  Fly   438 LVAVVILFVLSWLPLYVIFARIKFGSDISQEEFEILKKVMPVAQ---------WLGSSNSCINPI 493
            |.::|..|.|.||||.| |..|          |:...:.:||.|         ....:::|:||:
Zfish   253 LASIVAAFALCWLPLNV-FNTI----------FDWNHEAIPVCQHDAIFSACHLTAMASTCVNPV 306

  Fly   494 LYS-VNKKYRRGFAAIIKSRSCCGRLRYYDNVAIASSTTSTRKSSHYHQNSSRKSPSSKGNAVSY 557
            :|. :|..:::...:::....|.|....|::..:::.:|...|.|..          |.|:|.:|
Zfish   307 IYGFLNNNFQKELKSLLSRCRCWGPAESYESFPLSTVSTGITKGSIL----------SNGSASTY 361

  Fly   558 -IYEHNSLRR 566
             .::.|||.:
Zfish   362 QPHKKNSLEQ 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	105/325 (32%)
		TM helix 1	210..236	CDD:320124	9/25 (36%)
		TM helix 2	243..269	CDD:320124	16/25 (64%)
		TM helix 3	281..311	CDD:320124	11/34 (32%)
		TM helix 4	322..340	CDD:320124	4/17 (24%)
		TM helix 5	379..404	CDD:320124	10/25 (40%)
		TM helix 6	429..459	CDD:320124	14/31 (45%)
		TM helix 7	474..498	CDD:320124	7/33 (21%)
npy8br	NP_571511.1	7tmA_NPY4R	26..319	CDD:320519	105/325 (32%)
		TM helix 1	27..53	CDD:320519	9/25 (36%)
		TM helix 2	60..85	CDD:320519	15/24 (63%)
		TM helix 3	98..128	CDD:320519	10/29 (34%)
		TM helix 4	139..160	CDD:320519	5/20 (25%)
		TM helix 5	195..224	CDD:320519	10/28 (36%)
		TM helix 6	244..274	CDD:320519	14/40 (35%)
		TM helix 7	287..312	CDD:320519	4/24 (17%)