Protein Alignment SIFaR and Qrfprl

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_780733.2
• Gene: Qrfprl / 243407
• MGIID: 2441881
• Length: 416
• Species: Mus musculus
• Alignment Length: 395
• Identity: 114/395 - (28%)
• Similarity: 202/395 - (51%)
• Gaps: 69/395 - (17%)

  Fly   195 FGFDPLY-------RHSLAMSMVYCVAYIVVFLVGLIGNSFVIAVVLRAPRMRTVTNYFIVNLAI 252
            :|..||.       |..||:.:|    .:::|.:.|.||:.|:.||.|:..||||||.||.:||:
Mouse    28 YGLRPLVLTPQLPARARLALLLV----GMLIFALALFGNALVVYVVTRSKAMRTVTNIFICSLAL 88

  Fly   253 ADILVIVFCLPATLIGNIFVPWMLGWLMCKFVPYIQGVSVAASVYSLIAVSLDRFIAIWWPLK-- 315
            :|:|::.||:|.|::.|:...|:.|..:||.||::|..::...:.::..::::|...:..|.|
Mouse    89 SDLLIVFFCIPVTMLQNVSDTWLGGAFICKMVPFVQCTAIVTEILTMTCIAVERHQGLVHPFKMK 153

  Fly   316 -QMTKRRARIMIIGIWVIALVTTIP-WLLFFDLVPAEEVFSDALVSAYSQPQFLCQEVWPPGTDG 378
             |.|.:||..|:..:|::|::...| |     .|...|:..|.|   |.:....|.|.|......
Mouse   154 RQYTNQRAFTMLGVVWLVAIIIGSPMW-----HVQRLEIKYDFL---YEKEHICCLEEWSSPVHQ 210

  Fly   379 NLY--FLLANLVACYLLPMSLITLCYVLI----WIKVS------TRSIPGESKDAQMDRMQQKSK 431
            .:|  |:|..|   :|||:.|:::.|..|    |||..      .|:|.|:    :|.::.:|.|
Mouse   211 KIYTTFILVTL---FLLPLLLLSVLYGKIGYELWIKKRIGDGSVLRTIHGK----EMFKIARKKK 268

  Fly   432 VKVIKMLVAVVILFVLSWLPLYVIFARIKFGSDISQEEFEI-LKKVMPVAQWLGSSNSCINPILY 495
            ..|| |:|.||:||.:.|.|.:::...|:: |:..:|..|: :|.:..:.|.:|..||..|||:|
Mouse   269 RAVI-MMVTVVVLFAVCWAPFHIVHMMIEY-SNFEKEYDEVTIKMIFAIVQIIGFFNSICNPIIY 331

  Fly   496 S-VNKKYRRGFAAIIKSRSC-CGRLRYYDNVAIASSTTSTRKSSH-----YHQN---SSRKSP-S 549
            : :|:.:::.|.:.:    | |         .:..:.:|.||...     .|:.   ::|::| .
Mouse   332 ALMNENFKKNFVSAV----CYC---------IVKETPSSARKHGSSGAMVMHRRAKLAARENPVE 383

  Fly   550 SKGNA 554
            .||.|
Mouse   384 IKGEA 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	96/313 (31%)
		TM helix 1	210..236	CDD:320124	8/25 (32%)
		TM helix 2	243..269	CDD:320124	12/25 (48%)
		TM helix 3	281..311	CDD:320124	6/29 (21%)
		TM helix 4	322..340	CDD:320124	5/18 (28%)
		TM helix 5	379..404	CDD:320124	9/26 (35%)
		TM helix 6	429..459	CDD:320124	12/29 (41%)
		TM helix 7	474..498	CDD:320124	9/24 (38%)
Qrfprl	NP_780733.2	7tmA_QRFPR	45..342	CDD:320333	98/317 (31%)
		TM helix 1	46..72	CDD:320333	9/29 (31%)
		TM helix 2	79..105	CDD:320333	12/25 (48%)
		TM helix 3	117..147	CDD:320333	6/29 (21%)
		TM helix 4	160..181	CDD:320333	7/25 (28%)
		TM helix 5	210..235	CDD:320333	9/27 (33%)
		TM helix 6	265..295	CDD:320333	12/30 (40%)
		TM helix 7	310..335	CDD:320333	9/24 (38%)