Protein Alignment SIFaR and Npbwr1

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_034472.1
• Gene: Npbwr1 / 226304
• MGIID: 891989
• Length: 329
• Species: Mus musculus
• Alignment Length: 313
• Identity: 91/313 - (29%)
• Similarity: 153/313 - (48%)
• Gaps: 40/313 - (12%)

  Fly   213 VAYIVVFLVGLIGNSFVIAVVLRAPRMRTVTNYFIVNLAIADILVIVFCLPATLIGNIFVPWMLG 277
            |.|.|:..|||.|||.|:.|:||.|||:||||.||:||||||.| ....||..:...:...|..|
Mouse    44 VVYGVICAVGLAGNSAVLYVLLRTPRMKTVTNVFILNLAIADEL-FTLVLPINIADFLLRRWPFG 107

  Fly   278 WLMCKFVPYIQGVSVAASVYSLIAVSLDRFIAIWWPLKQMTKRR--------ARIMIIGIWVIAL 334
            .:|||.:..:...:..:|:|.|..:|.||::.:   |.....||        ||.:.:.:|.:..
Mouse   108 EVMCKLIVAVDQYNTFSSLYFLAVMSADRYLVV---LATAESRRVSGRTYGAARAVSLAVWALVT 169

  Fly   335 VTTIPWLLFFDLVPAEEVFSDALVSAYSQPQFLCQEVWPPGTDGNLYFLLANLVACYLLPMSLIT 399
            :..:|:.:|..|  .||......|..:.||    :..|  .....||    .||..:.:|::  |
Mouse   170 LVVLPFAVFARL--DEEQGRRQCVLVFPQP----EAFW--WRASRLY----TLVLGFAIPVT--T 220

  Fly   400 LCYVLIWIKVSTRSIPGESKDAQMDRMQQKSKVKVIKMLVAVVILFVLSWLPLYVIFARIKFGSD 464
            :|.:...:....|:|..:|....:||    :|.:|..::.|::.:.:|.|.| |.:...:...:|
Mouse   221 ICALYTTLLCRLRAIQLDSHAKALDR----AKKRVTLLVAAILAVCLLCWTP-YHLSTIVALTTD 280

  Fly   465 ISQEEFEILKKVMPVAQWLGS---SNSCINPILYS-VNKKYRRGFAAIIKSRS 513
            :.|...     |:.::.::.|   :|||:||.||: ::..:||....::..||
Mouse   281 LPQTPL-----VIGISYFITSLSYANSCLNPFLYAFLDDSFRRSLRQLVSCRS 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	89/303 (29%)
		TM helix 1	210..236	CDD:320124	12/22 (55%)
		TM helix 2	243..269	CDD:320124	13/25 (52%)
		TM helix 3	281..311	CDD:320124	8/29 (28%)
		TM helix 4	322..340	CDD:320124	3/17 (18%)
		TM helix 5	379..404	CDD:320124	7/24 (29%)
		TM helix 6	429..459	CDD:320124	7/29 (24%)
		TM helix 7	474..498	CDD:320124	9/27 (33%)
Npbwr1	NP_034472.1	7tmA_NPBWR	40..320	CDD:320215	89/303 (29%)
		TM helix 1	41..67	CDD:320215	12/22 (55%)
		TM helix 2	74..100	CDD:320215	13/26 (50%)
		TM helix 3	111..141	CDD:320215	8/32 (25%)
		TM helix 4	155..177	CDD:320215	4/21 (19%)
		TM helix 5	202..231	CDD:320215	7/34 (21%)
		TM helix 6	246..276	CDD:320215	8/34 (24%)
		TM helix 7	288..313	CDD:320215	8/24 (33%)