Protein Alignment SIFaR and Sstr3

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_033244.2
• Gene: Sstr3 / 20607
• MGIID: 98329
• Length: 428
• Species: Mus musculus
• Alignment Length: 484
• Identity: 125/484 - (25%)
• Similarity: 211/484 - (43%)
• Gaps: 88/484 - (18%)

  Fly   165 ATTSLISAAAATKSYNDSALRWEQLD---GSVDFGFDPLYRHSLAMS-MVYCVAYIVVFLVGLIG 225
            ||.:..|:...|....:::..| .||   |:...|..   ...||:| ::..:.|:||.:|||:|
Mouse     2 ATVTYPSSEPTTLDPGNASSTW-PLDTTLGNTSAGAS---LTGLAVSGILISLVYLVVCVVGLLG 62

  Fly   226 NSFVIAVVLRAPRMRTVTNYFIVNLAIADILVIVFCLPATLIGNIFVPWMLGWLMCKFVPYIQGV 290
            ||.||.||||.....:||:.:|:|||:||.| .:..||.....|....|..|.|||:.|..:.|:
Mouse    63 NSLVIYVVLRHTSSPSVTSVYILNLALADEL-FMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGI 126

  Fly   291 SVAASVYSLIAVSLDRFIAIWWPLKQMTKRR---ARIMIIGIWVIALVTTIPWLLFFDLVPAEEV 352
            :...|::.|..:|:||::|:..|.:....|.   ||.:...:||.:.|..:|.::|
Mouse   127 NQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVF--------- 182

  Fly   353 FSDALVSAYSQPQFLCQEVWP-PGTDGNLYFLLANLVACYLLPMSLITLCYVLIWIKV--STRSI 414
                  |...:....|...|| |.......|::......:..|:.:|.|||:||.:||  :||.:
Mouse   183 ------SGVPRGMSTCHMQWPEPAAAWRTAFIIYTAALGFFGPLLVICLCYLLIVVKVRSTTRRV 241

  Fly   415 PGES---KDAQMDRMQQKSKVKVIKMLVAVVILFVLSWLPLYVIFARIKFGSDISQEEFEILKKV 476
            ...|   ..|...:.:::|:.:|.:|:||||.||||.|:|.|::               .|:..|
Mouse   242 RAPSCQWVQAPACQRRRRSERRVTRMVVAVVALFVLCWMPFYLL---------------NIVNVV 291

  Fly   477 MPVAQ------------WLGSSNSCINPILYS-VNKKYRRGFAAIIKSRSCCGRLRYYDNVAIAS 528
            .|:.:            .|..:|||.|||||. ::.::::||..|:...|  .|:|..:.   .|
Mouse   292 CPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRILLRPS--RRIRSQEP---GS 351

  Fly   529 STTSTRKSSHYHQNSSRKSPSSKGNAVSYIYEHNSLRRHNMMLKQDSNLSQQMLLKQDSHGSRQF 593
            ......:.....:...|:....:                .|...|:.|.....:.:..:.|
Mouse   352 GPPEKTEEEEDEEEEERREEEER----------------RMQRGQEMNGRLSQIAQAGTSG---- 396

  Fly   594 LIKQESSCSDASGIRRPLCQQDSNGSKVS 622
              :|...|:..:..::.|.|:.:.|.|.|
Mouse   397 --QQPRPCTGTAKEQQLLPQEATAGDKAS 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	94/317 (30%)
		TM helix 1	210..236	CDD:320124	14/25 (56%)
		TM helix 2	243..269	CDD:320124	10/25 (40%)
		TM helix 3	281..311	CDD:320124	9/29 (31%)
		TM helix 4	322..340	CDD:320124	5/17 (29%)
		TM helix 5	379..404	CDD:320124	6/24 (25%)
		TM helix 6	429..459	CDD:320124	14/29 (48%)
		TM helix 7	474..498	CDD:320124	11/36 (31%)
Sstr3	NP_033244.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		4/17 (24%)
		7tm_GPCRs	46..333	CDD:475119	94/317 (30%)
		TM helix 1	48..72	CDD:410628	13/23 (57%)
		TM helix 2	81..102	CDD:410628	9/21 (43%)
		TM helix 3	118..140	CDD:410628	4/21 (19%)
		TM helix 4	163..179	CDD:410628	3/15 (20%)
		TM helix 5	205..228	CDD:410628	5/22 (23%)
		TM helix 6	265..287	CDD:410628	12/36 (33%)
		TM helix 7	301..326	CDD:410628	9/24 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	344..428		14/105 (13%)