Protein Alignment SIFaR and ckr-1

DIOPT Version :9

• Sequence 1: NP_001163674.1
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_491918.3
• Gene: ckr-1 / 188774
• WormBaseID: WBGene00020712
• Length: 421
• Species: Caenorhabditis elegans
• Alignment Length: 446
• Identity: 107/446 - (23%)
• Similarity: 176/446 - (39%)
• Gaps: 158/446 - (35%)

  Fly   215 YIVVFLVGLIGNSFVIAVVL-RAPRMRTVTNYFIVNLAIADILVIVFCLPATLIGNIFVPWMLGW 278
            :::..::.|:||:.||..:| ::.|.|::||::::|||.||:|..:.|:|:||:|.:...|:||.
 Worm    20 FLLCLILSLLGNAIVILTILGKSHRSRSITNFYLLNLAFADLLRSIICIPSTLLGELTQCWLLGA 84

  Fly   279 LMCKFVPYIQGVSVAASVYSLIAVSLDRFIAIWWPL---KQMTKRRARIMIIGIWVIALVTTIPW 340
            .|||.|.::|.|.|.||.|:|..::::|:.||..||   |..||:||.|.|..:|..:....:..
 Worm    85 AMCKIVAFLQPVGVCASAYTLAVIAIERYYAICRPLESRKWQTKKRALITISLVWCFSFSANLTS 149

  Fly   341 LLFFDLVPAEEVFSDALVSAYSQPQFLCQEVWPPGTDGNLYFLLANLVACYLL---PMSLITLCY 402
            |..:|..|.               :|.|.     .|.|.|...:..|...:.|   |::|:...|
 Worm   150 LFLYDANPG---------------KFTCD-----STKGPLVDFIYQLYLTFTLLFVPLALMVGLY 194

  Fly   403 --VLI------------------------------W----------IKVSTR------------- 412
              |:|                              |          :||.::
 Worm   195 GNVIITLNTAINSDHPTVEQQMIEKTLPSRASFSDWFVSAVQRVPSMKVVSKTFQFKEKNSLSIP 259

  Fly   413 ------------------SIPGESKDAQM---DRMQQK---SKVKVIKMLVAVVILFVLSWLPLY 453
                              |.|..|.|..|   ...|:|   :|.||.:||:.:||:|...|:|.|
 Worm   260 QTSGLSVRPSRSSFSSFFSTPRGSFDVTMLLRSTNQEKILIAKKKVTRMLITLVIVFAFCWVPSY 324

  Fly   454 VIFARIKFGSDISQEEFEILKKVMPVAQW---LGSS-------NSCINPILYS-VNKKYRRGFAA 507
            :.:..::            :.::.....|   |.||       :|..|||.|. :||.:|....|
 Worm   325 LYWLLLR------------MAELAATDLWNPGLNSSLTIMTYISSLANPITYCFMNKSFRSSVLA 377

  Fly   508 IIKSR-----SCCGRLRYYDNVAIASSTTSTRKSSHYHQNSSRKSPSSKGNAVSYI 558
            ..:.:     :.|..|                        .:||||||..:|:..|
 Worm   378 YCRPKPKRPLTRCSAL------------------------PTRKSPSSPTHAIPMI 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_001163674.1	7tm_4	216..>443	CDD:304433	78/312 (25%)
		7tm_1	225..495	CDD:278431	91/365 (25%)
ckr-1	NP_491918.3	7tmA_CCKR-like	30..375	CDD:320124	95/376 (25%)
		TM helix 2	50..72	CDD:320124	9/21 (43%)
		TM helix 3	88..110	CDD:320124	9/21 (43%)
		TM helix 4	133..149	CDD:320124	3/15 (20%)
		TM helix 5	172..195	CDD:320124	4/22 (18%)
		TM helix 6	303..328	CDD:320124	10/24 (42%)
		TM helix 7	343..368	CDD:320124	8/24 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870