Protein Alignment SIFaR and npr-11

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_508234.2
• Gene: npr-11 / 182921
• WormBaseID: WBGene00016110
• Length: 402
• Species: Caenorhabditis elegans
• Alignment Length: 349
• Identity: 96/349 - (27%)
• Similarity: 160/349 - (45%)
• Gaps: 46/349 - (13%)

  Fly   214 AYIVVFLVGLIGNSFVIAVVLRAPRMRTVTNYFIVNLAIADILVIVFCLPATLIGNIFVPWMLGW 278
            ||:::.|.|.|||...|.||:..|.|||..|:||:|||::|..|.:...|.||...:::.|....
 Worm    45 AYMLIILFGAIGNFLTIIVVILNPAMRTTRNFFILNLALSDFFVCIVTAPTTLYTVLYMFWPFSR 109

  Fly   279 LMCKFVPYIQGVSVAASVYSLIAVSLDRFIAIWWPLKQMTKRRARI-MIIGIWVIALVTTIPWLL 342
            .:||....:||.::..|.:|:.::::||::.|.:|.|:..::.... ..|.||||:|:..:|.|.
 Worm   110 TLCKIAGSLQGFNIFLSTFSIASIAVDRYVLIIFPTKRERQQNLSFCFFIMIWVISLILAVPLLQ 174

  Fly   343 FFDLVPAEEVFSD-----ALVSAYSQPQFLCQEVWPPGTDGNLYFLLANLVACYLLPMSLITLCY 402
            ..||.|   ||.:     ||...:.|     .|:|.........:.||.|:..|..|:..:...|
 Worm   175 ASDLTP---VFVEPSCDLALYICHEQ-----NEIWEKMIISKGTYTLAVLITQYAFPLFSLVFAY 231

  Fly   403 VLIWIKVSTR------SIPGESKDAQMDRMQQKSKVKVIKMLVAVVILFVLSWLPLYV--IFARI 459
            ..|..::..|      ::...:..:|..|...:.:.:...:||.||.:|.::||||.|  ||...
 Worm   232 SRIAHRMKLRFANRNQNVTTNTNTSQRRRSVVERQRRTHLLLVCVVAVFAVAWLPLNVFHIFNTF 296

  Fly   460 KFGSDISQEEFEILKKVMPVAQWLGSSNSCINPILYS-VNKKYRRGFAAIIKSRSCCGRLRYYDN 523
            :..:..|...|.|       ...|...::|:||::|: .|..:|..|            :..:|.
 Worm   297 ELVNSFSVTTFSI-------CHCLAMCSACLNPLIYAFFNHNFRIEF------------MHLFDR 342

  Fly   524 VAIASSTTSTRKSSHYHQNSSRKS 547
            |.:    .|.|......|.|.:||
 Worm   343 VGL----RSLRVVIFGEQESLKKS 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	87/305 (29%)
		TM helix 1	210..236	CDD:320124	10/21 (48%)
		TM helix 2	243..269	CDD:320124	11/25 (44%)
		TM helix 3	281..311	CDD:320124	8/29 (28%)
		TM helix 4	322..340	CDD:320124	6/18 (33%)
		TM helix 5	379..404	CDD:320124	6/24 (25%)
		TM helix 6	429..459	CDD:320124	12/31 (39%)
		TM helix 7	474..498	CDD:320124	5/24 (21%)
npr-11	NP_508234.2	7tmA_NPYR-like	40..336	CDD:320331	87/305 (29%)
		TM helix 1	41..67	CDD:320331	10/21 (48%)
		TM helix 2	74..99	CDD:320331	11/24 (46%)
		TM helix 3	112..142	CDD:320331	8/29 (28%)
		TM helix 4	153..174	CDD:320331	7/20 (35%)
		TM helix 5	208..237	CDD:320331	7/28 (25%)
		TM helix 6	264..294	CDD:320331	11/29 (38%)
		TM helix 7	304..329	CDD:320331	7/31 (23%)