Protein Alignment SIFaR and LOC1281799

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_061497177.1
• Gene: LOC1281799 / 1281799
• VectorBaseID: AGAMI1_009161
• Length: 472
• Species: Anopheles gambiae
• Alignment Length: 469
• Identity: 179/469 - (38%)
• Similarity: 260/469 - (55%)
• Gaps: 62/469 - (13%)

  Fly   102 TDTLLGTVLTTATATVAP--AASSLLATLAATTTASARGSLAGKSL------AIADATSSTYYSN 158
            |:|...:.::|...|||.  |...|...:..|..|:|..:|.|:.|      ....|....:..:
Mosquito     8 TETEPPSAMSTTVVTVATLLAERCLGCAINYTGAAAATANLPGERLQSDFGRPTTPAPRHNWTWS 72

  Fly   159 LLNLSPATTSLISAAAATKSYNDSALRWEQLDGSVDFGFDPLY--RHSLAMSMVYCVAYIVVFLV 221
            .||||           |.:.|       :..||  ::..||.|  |:|:..:::..|||.:||::
Mosquito    73 YLNLS-----------APQQY-------DTYDG--EYEIDPAYQLRYSVLGTVLLTVAYALVFIL 117

  Fly   222 GLIGNSFVIAVVLRAPRMRTVTNYFIVNLAIADILVIVFCLPATLIGNIFVPWMLGWLMCKFVPY 286
            ||:||..|:.||.::..||:.||.||||||.||:||...|||.|||||::..|:||...||.|.|
Mosquito   118 GLLGNISVVIVVKKSTMMRSPTNRFIVNLAYADLLVNFLCLPFTLIGNLYPAWILGVFFCKGVSY 182

  Fly   287 IQGVSVAASVYSLIAVSLDRFIAIWWPLK-QMTKRRARIMIIGIWVIALVTTIPWLLFFDLVPAE 350
            :|||||:|||.:|:|:|::|..||.:|:. .:|.|:.|:::..||.|||...:|||..|.|.|.
Mosquito   183 LQGVSVSASVNTLMAISIERCFAISFPISGTITTRQYRLIVTIIWFIALSINLPWLFVFTLRPI- 246

  Fly   351 EVFSDALVSAYSQPQFLCQEVWPPGTDGNLYFLLANLVACYLLPMSLITLCYVLIWIKVSTRSIP 415
                 .:..:.:|   :|.|:||.....:.|||.|||..|||.|:.:|::|||:||..|:.|::|
Mosquito   247 -----GIPGSIAQ---ICTELWPTPASESWYFLFANLFFCYLGPLIVISICYVIIWKNVAYRNLP 303

  Fly   416 GESKDAQMDRMQQKSKVKVIKMLVAVVILFVLSWLPLYVIFARIKFGSDISQEEF--EILKKVMP 478
            .|....:.:.:..:||||||||:..|:|.|.:||||||.||..:||..|:..:|.  ..:..::|
Mosquito   304 REMIINRKNDVFNRSKVKVIKMVFVVIITFAISWLPLYAIFCFVKFAGDLVYDETVQSFILNILP 368

  Fly   479 VAQWLGSSNSCINPILYS-VNKKYRRGFAAIIKSRSCC-------------GRLR----YYDNVA 525
            ||||||:||||||||||: :|:|:|.||..:.  .|||             |||.    |...|.
Mosquito   369 VAQWLGASNSCINPILYAFMNRKFRAGFKKLF--HSCCTTDEDDWDLPTTVGRLEEKDLYLRRVR 431

  Fly   526 IASSTTSTRKSSHY 539
            ..|:....:...||
Mosquito   432 SFSNGKQHQTLLHY 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	138/299 (46%)
		TM helix 1	210..236	CDD:320124	12/25 (48%)
		TM helix 2	243..269	CDD:320124	18/25 (72%)
		TM helix 3	281..311	CDD:320124	17/29 (59%)
		TM helix 4	322..340	CDD:320124	6/17 (35%)
		TM helix 5	379..404	CDD:320124	13/24 (54%)
		TM helix 6	429..459	CDD:320124	19/29 (66%)
		TM helix 7	474..498	CDD:320124	17/24 (71%)
LOC1281799	XP_061497177.1	None