Protein Alignment SIFaR and TkR86C

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_061501551.1
• Gene: TkR86C / 1273136
• VectorBaseID: AGAMI1_012898
• Length: 497
• Species: Anopheles gambiae
• Alignment Length: 517
• Identity: 135/517 - (26%)
• Similarity: 231/517 - (44%)
• Gaps: 111/517 - (21%)

  Fly    95 KLNNSAITDTLLGTVLTTATATVAPAASSLLATLAATTTASARGSLAGKSLAIADATSSTYYSNL 159
            :||.:.:.| :||.::|.:...| |.::.|| ||....|.           .:...|.|.|
Mosquito    34 ELNRTEVLD-VLGEMITRSRGYV-PKSTDLL-TLREFITE-----------CLFPTTKSPY---- 80

  Fly   160 LNLSPATTSLISAAAATKSYNDSALRWEQLDGSVDFGFDPLYRHSLAMSMVYCVAYIVVFLVGLI 224
                                   .|.|:                   :...:.|.:..:.||.:.
Mosquito    81 -----------------------ELPWQ-------------------LKTAWGVVFGAMLLVAIT 103

  Fly   225 GNSFVIAVVLRAPRMRTVTNYFIVNLAIADILVIVFCLPATLIGNIFVPWMLGWLMCKFVPYIQG 289
            ||..|:.:||...|||||||||::||::||:|:.........|..:...|..|.:.|....::..
Mosquito   104 GNCIVLWIVLAHRRMRTVTNYFLLNLSVADLLMSSLNCSFNFIFMLNSDWPFGSVYCTINNFMAN 168

  Fly   290 VSVAASVYSLIAVSLDRFIAIWWPLKQMTKR-RARIMIIGIWVIALVTTIPWLLFFDLVPAEEVF 353
            :|||:||::|:|:|.||:|||..||:..|.| :|||.::.||.::.|...|.|:          :
Mosquito   169 MSVASSVFTLVAISFDRYIAIVHPLRHRTSRKKARIFLLIIWALSCVLAAPCLM----------Y 223

  Fly   354 SDALVSAYS--QPQFLCQEVWP----PGTDGNLYFLLANLVACYLLPMSLITLCYVL----IWIK 408
            |..:...|:  :.:.:|..:||    |.:..:..:.|..|:..|.:||.::.:||.|    :|
Mosquito   224 STVMTKRYNNGKTRTVCYMLWPDGRYPTSMADYIYNLVFLILTYGIPMLIMIVCYSLMGRELW-- 286

  Fly   409 VSTRSIPGESKDAQMDRMQQKSKVKVIKMLVAVVILFVLSWLPLYVIFARIKFGSDISQEEFEIL 473
             .:||| ||..:.|::.|  |||.||::|.:.||.:|.:.|||.::.|......:.::...:  :
Mosquito   287 -GSRSI-GEHTERQLESM--KSKKKVVRMFIIVVTIFAICWLPYHLFFVYAYHNNQMTSSSY--V 345

  Fly   474 KKVMPVAQWLGSSNSCINPILYS-VNKKYRRGFAAIIKSRSCC-----GRLRYYDNV--AIASST 530
            :::.....||..||:.:|||:|. :|.::|..|..||  ..||     .|:|  |.|  .:..:.
Mosquito   346 QQLYLGFYWLAMSNAMVNPIIYYWMNGRFRVYFQEII--CFCCLQFINSRMR--DGVPQGVLLNK 406

  Fly   531 TSTRKSSHYHQNSSRKSPSSKGNAVSYIYEHNSLRRHNMM--LKQDSNLSQQMLLKQDSHGS 590
            .|..:...|.        |.:..:||..:...|...:.|.  |.:.::|...:|....:.||
Mosquito   407 NSNSELGRYR--------SYRPRSVSVRWRPPSTEEYRMRTGLPRPAHLGVNVLESAANGGS 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	96/307 (31%)
		TM helix 1	210..236	CDD:320124	8/25 (32%)
		TM helix 2	243..269	CDD:320124	10/25 (40%)
		TM helix 3	281..311	CDD:320124	13/29 (45%)
		TM helix 4	322..340	CDD:320124	6/17 (35%)
		TM helix 5	379..404	CDD:320124	7/24 (29%)
		TM helix 6	429..459	CDD:320124	13/29 (45%)
		TM helix 7	474..498	CDD:320124	8/24 (33%)
TkR86C	XP_061501551.1	None