Protein Alignment SIFaR and npy2r

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_004911210.1
• Gene: npy2r / 100498351
• XenbaseID: XB-GENE-983413
• Length: 408
• Species: Xenopus tropicalis
• Alignment Length: 381
• Identity: 119/381 - (31%)
• Similarity: 187/381 - (49%)
• Gaps: 43/381 - (11%)

  Fly   172 AAAATKSYNDSALRWEQLDGSVDFGFDPLYRHSLAMSMVYCVAYIVVFLVGLIGNSFVIAVVLRA 236
            ||..|..||| ..:.|.:|          ....|::.:|..:||..:.|:|::|||.||.||::.
 Frog    48 AAGLTTPYND-LTKPELID----------ITKLLSVQVVLILAYSSIILLGVLGNSLVIYVVIKF 101

  Fly   237 PRMRTVTNYFIVNLAIADILVIVFCLPATLIGNIFVPWMLGWLMCKFVPYIQGVSVAASVYSLIA 301
            ..||||||:||||||::|::|...|||.||:..:...|..|.::|..|.|.||::|..|..:|:.
 Frog   102 KTMRTVTNFFIVNLAVSDLMVNTLCLPFTLVYTLLDDWKFGTVLCHLVTYSQGLAVQVSTVTLMV 166

  Fly   302 VSLDRFIAIWWPLKQMTKRRARIMIIGI-WVIALVTTIPWLLFFDLVPAEEVFSDALVSAYSQPQ 365
            ::|||...|.:.|:.....:...||||| ||.:.:...|..:|       :.:|..::|:..|.|
 Frog   167 IALDRHRCIVYHLESKISTKICFMIIGITWVCSALLASPLAIF-------KEYSVIVISSDFQIQ 224

  Fly   366 FLCQEVWPPG--TDGNLYFLLANLVACYLLPMSLITLCYVLIWIKVSTRSIPGESKDAQMDRMQQ 428
             .|.|.||.|  ..|.:| .::.|:..|::|:::|:..|:.||.|:.....||...|....|.:
 Frog   225 -ACSERWPVGDLNYGTIY-SISMLLIQYIVPLAIISYAYIRIWTKLKNHVSPGGGNDHYHQRRR- 286

  Fly   429 KSKVKVIKMLVAVVILFVLSWLPLYVIFARIKFGSDISQEEFEI--LKKVMPVAQWLGSSNSCIN 491
                |..|||||||::|.:.|||    |...:..|||..:..::  .|.:..:...:...::..|
 Frog   287 ----KTTKMLVAVVVVFAVCWLP----FHAFQLASDIDGKVLDLNEYKLIYTIFHVIAMCSTFAN 343

  Fly   492 PILYS-VNKKYRRGFAAIIKSRSCCGRLRYYDNVAI--------ASSTTSTRKSSH 538
            |:||. :|..||..|....|.......:....:|||        ......|..:||
 Frog   344 PLLYGWMNNNYRTAFLTAFKCEQRMDSIHPEVSVAIQLKKKQLEVKEINGTSDNSH 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	102/301 (34%)
		TM helix 1	210..236	CDD:320124	12/25 (48%)
		TM helix 2	243..269	CDD:320124	15/25 (60%)
		TM helix 3	281..311	CDD:320124	11/29 (38%)
		TM helix 4	322..340	CDD:320124	7/18 (39%)
		TM helix 5	379..404	CDD:320124	6/24 (25%)
		TM helix 6	429..459	CDD:320124	13/29 (45%)
		TM helix 7	474..498	CDD:320124	5/24 (21%)
npy2r	XP_004911210.1	7tmA_NPY2R	74..358	CDD:320521	102/301 (34%)
		TM helix 1	75..101	CDD:320521	12/25 (48%)
		TM helix 2	108..133	CDD:320521	15/24 (63%)
		TM helix 3	146..176	CDD:320521	11/29 (38%)
		TM helix 4	187..208	CDD:320521	8/20 (40%)
		TM helix 5	238..267	CDD:320521	9/29 (31%)
		TM helix 6	283..313	CDD:320521	14/38 (37%)
		TM helix 7	326..351	CDD:320521	5/24 (21%)