Protein Alignment SIFaR and npffr2

DIOPT Version :10

• Sequence 1: NP_650966.2
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_002940397.1
• Gene: npffr2 / 100498122
• XenbaseID: XB-GENE-994428
• Length: 426
• Species: Xenopus tropicalis
• Alignment Length: 444
• Identity: 147/444 - (33%)
• Similarity: 247/444 - (55%)
• Gaps: 44/444 - (9%)

  Fly   177 KSYNDSALRWEQLDGS-VDFGFDPLYRHSLAMSMVYCVAYIVVFLVGLIGNSFVIAVVLRAPRMR 240
            ||.| ..|.:|:.:.: |||     |.|..:::.|:..:|:::|::.::||..|..:||.:..||
 Frog    17 KSLN-KTLNYEEPNITYVDF-----YLHRPSVAAVFIASYLLIFILCMLGNGVVCFIVLSSKHMR 75

  Fly   241 TVTNYFIVNLAIADILVIVFCLPATLIGNIFVPWMLGWLMCKFVPYIQGVSVAASVYSLIAVSLD 305
            ||||.||:||||:|:||.:||:|.||:.||...|..|..:||....:||:||:|||::|:|:::|
 Frog    76 TVTNLFILNLAISDLLVGIFCMPTTLLDNIIAGWPFGSTVCKMSGMVQGISVSASVFTLVAIAVD 140

  Fly   306 RFIAIWWPLKQ-MTKRRARIMIIGIWVIALVTTIPWLLFFDLVPAEEVFSDAL-VSAYSQPQFLC 368
            ||..|.:|.|| :|...|.::|:.|||:|:....|..: ...|..::.|...: .|..:.|.:.|
 Frog   141 RFRCIVYPFKQKLTISTAVVIIVVIWVLAIAIMCPSAV-MSHVKEDKNFRVVIGNSNQTNPIYWC 204

  Fly   369 QEVWPPGTDGNLY--FLLANLVACYLLPMSLITLCYVLIWIKVSTRSIPGESKDAQMDR-MQQKS 430
            :|.||......:|  .|.:|:   ||.|:|||.:.|..|.|.:....:..|:|:.|..| ...:.
 Frog   205 REDWPNPEMRKIYTTVLFSNI---YLAPLSLIVIMYARIGITLFKSELNVENKNHQQPRHAVSRR 266

  Fly   431 KVKVIKMLVAVVILFVLSWLPLYVIFARIKFGSDISQEEFEILK-KVMPVAQWLGSSNSCINPIL 494
            |.||||||:.:.:||:||||||:.:.....: ::::|.:::::. .:.|.|.||...||.||||:
 Frog   267 KQKVIKMLIIIALLFILSWLPLWTLMMLTDY-ANLTQNQYQMINIYIYPFAHWLAFFNSSINPII 330

  Fly   495 YS-VNKKYRRGFAAIIKSRSCCGRLRYYDNVAIASSTTSTRKSSHYHQNSSRKSPSSKGNAVSYI 558
            |. .|:.:||||.|..|.:.|...|.              |::.:.|:        ::|||:...
 Frog   331 YGFFNENFRRGFQAAFKLQLCSEELE--------------RRTMYSHR--------AQGNAILPA 373

  Fly   559 YEHNSLRRHNMMLKQDSNLSQQMLLKQDSHGSRQFLIKQE-SSCSDASGIRRPL 611
            ..||:.|:::...||.|:..:..  |:....|.|.||.:: ...|:.:||::.:
 Frog   374 ASHNTARQNSAFEKQSSDDKESD--KRKPLTSDQDLIMEDLEKFSNNNGIQKDM 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIFaR	NP_650966.2	7tmA_CCKR-like	209..505	CDD:320124	112/302 (37%)
		TM helix 1	210..236	CDD:320124	8/25 (32%)
		TM helix 2	243..269	CDD:320124	16/25 (64%)
		TM helix 3	281..311	CDD:320124	14/29 (48%)
		TM helix 4	322..340	CDD:320124	6/17 (35%)
		TM helix 5	379..404	CDD:320124	10/26 (38%)
		TM helix 6	429..459	CDD:320124	15/29 (52%)
		TM helix 7	474..498	CDD:320124	11/25 (44%)
npffr2	XP_002940397.1	7tmA_NPFFR2	44..342	CDD:320646	112/302 (37%)
		TM helix 1	45..71	CDD:320646	8/25 (32%)
		TM helix 2	78..104	CDD:320646	16/25 (64%)
		TM helix 3	116..146	CDD:320646	14/29 (48%)
		TM helix 4	157..178	CDD:320646	7/20 (35%)
		TM helix 5	214..243	CDD:320646	11/31 (35%)
		TM helix 6	265..295	CDD:320646	15/29 (52%)
		TM helix 7	310..335	CDD:320646	11/24 (46%)